CD74 Protein (Fc Tag)
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- Target See all CD74 Proteins
- CD74 (HLA-DR-gamma (CD74))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This CD74 protein is labelled with Fc Tag.
- Purpose
- Recombinant Human CD74(73-232) Protein with N-terminal human Fc tag
- Specificity
- HFc (Glu99-Ala330) CD74 (Gln73-Met232)
- Characteristics
- Extracellular Domain Protein
- Purification
- Purified from cell culture supernatant by affinity chromatography
- Purity
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
- Top Product
- Discover our top product CD74 Protein
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HLA-DR-gamma (CD74) (AA 73-232) protein (His tag)
CD74 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
HLA-DR-gamma (CD74) (AA 56-279) protein (His tag)CD74 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
HLA-DR-gamma (CD74) (AA 1-160) protein (GST tag)CD74 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
HLA-DR-gamma (CD74) protein (His tag,mFc Tag)CD74 Origin: Mouse Host: Human Cells Recombinant > 95 % as determined by SDS-PAGE
HLA-DR-gamma (CD74) (AA 73-232) protein (His tag)CD74 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- CD74 (HLA-DR-gamma (CD74))
- Alternative Name
- CD74 (CD74 Products)
- Background
- The protein encoded by this gene associates with class II major histocompatibility complex (MHC) and is an important chaperone that regulates antigen presentation for immune response. It also serves as cell surface receptor for the cytokine macrophage migration inhibitory factor (MIF) which, when bound to the encoded protein, initiates survival pathways and cell proliferation. This protein also interacts with amyloid precursor protein (APP) and suppresses the production of amyloid beta (Abeta). Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011]
- Molecular Weight
- predicted molecular mass of 44.4 kDa after removal of the signal peptide.The apparent molecular mass of hFc-CD74(73-232) is 55-70 kDa due to glycosylation.
- UniProt
- P04233
- Pathways
- Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Negative Regulation of intrinsic apoptotic Signaling, Cancer Immune Checkpoints
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