FZD4 Protein (AA 37-180) (Fc Tag)
-
- Target See all FZD4 Proteins
- FZD4 (Frizzled Family Receptor 4 (FZD4))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 37-180
- Origin
- Human
-
Source
- HEK-293 Cells
- Purification tag / Conjugate
- This FZD4 protein is labelled with Fc Tag.
- Purpose
- Recombinant Human FZD4 with C-terminal human Fc tag
- Specificity
- FZD4 (Phe37-Glu180) hFc (Glu99-Ala330)
- Characteristics
- Extracellular Domain Protein
- Purification
- Purified from cell culture supernatant by affinity chromatography
- Purity
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
- Top Product
- Discover our top product FZD4 Protein
-
-
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
-
- Target
- FZD4 (Frizzled Family Receptor 4 (FZD4))
- Alternative Name
- FZD4 (FZD4 Products)
- Synonyms
- CG4626 Protein, DFz4 Protein, Dfz4 Protein, Dm Fz4 Protein, Dmel\\CG4626 Protein, Fz4 Protein, anon-WO0170980.10 Protein, anon-WO0170980.11 Protein, fz1 Protein, zg01 Protein, CD344 Protein, EVR1 Protein, FEVR Protein, FZD4S Protein, Fz-4 Protein, FzE4 Protein, GPCR Protein, hFz4 Protein, frizzled4 Protein, fz4 Protein, FZ-4 Protein, frizzled 4 Protein, frizzled class receptor 4 Protein, frizzled-4 Protein, frizzled class receptor 4 S homeolog Protein, fz4 Protein, fzd4 Protein, Tsp_10376 Protein, FZD4 Protein, Fzd4 Protein, fzd4.S Protein
- Background
- This gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This protein may play a role as a positive regulator of the Wingless type MMTV integration site signaling pathway. A transcript variant retaining intronic sequence and encoding a shorter isoform has been described, however, its expression is not supported by other experimental evidence. [provided by RefSeq, Jul 2008]
- Molecular Weight
- predicted molecular mass of 42.4 kDa after removal of the signal peptide. The apparent molecular mass of FZD4-hFc is 55-70 kDa due to glycosylation.
- UniProt
- Q9ULV1
- Pathways
- WNT Signaling, Hormone Transport, Sensory Perception of Sound
-