DPP4 Protein (AA 34-766) (His tag)

Catalog No. ABIN7092742

Product Details

Target: DPP4 (Dipeptidyl-Peptidase 4 (DPP4))

Protein Type: Recombinant

Protein Characteristics: AA 34-766

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This DPP4 protein is labelled with His tag.

Purpose: Recombinant Human CD26 with C-terminal 6xHis tag

Specificity: CD26 (Asp34-Pro766) 6xHis tag

Characteristics: Extracellular Domain Protein

Purification: Purified from cell culture supernatant by affinity chromatography

Purity: The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Storage: -20 °C,-80 °C

Storage Comment: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Expiry Date: 12 months

Target Details

Target: DPP4 (Dipeptidyl-Peptidase 4 (DPP4))

Alternative Name: CD26 (DPP4 Products)

Synonyms: ADABP Protein, ADCP2 Protein, CD26 Protein, DPPIV Protein, TP103 Protein, MGC81966 Protein, MOP9.8 Protein, MOP9_8 Protein, DPP4 Protein, si:ch73-2d23.3 Protein, Cd26 Protein, Dpp-4 Protein, THAM Protein, dipeptidyl peptidase 4 Protein, dipeptidyl-peptidase 4 S homeolog Protein, prolyl oligopeptidase family protein Protein, dipeptidyl-peptidase 4 Protein, dipeptidylpeptidase 4 Protein, DPP4 Protein, dpp4.S Protein, AT5G24260 Protein, dpp4 Protein, Dpp4 Protein

Background: The DPP4 gene encodes dipeptidyl peptidase 4, which is identical to adenosine deaminase complexing protein-2, and to the T-cell activation antigen CD26. It is an intrinsic type II transmembrane glycoprotein and a serine exopeptidase that cleaves X-proline dipeptides from the N-terminus of polypeptides. Dipeptidyl peptidase 4 is highly involved in glucose and insulin metabolism, as well as in immune regulation. This protein was shown to be a functional receptor for Middle East respiratory syndrome coronavirus (MERS-CoV), and protein modeling suggests that it may play a similar role with SARS-CoV-2, the virus responsible for COVID-19. [provided by RefSeq, Apr 2020]

Molecular Weight: predicted molecular mass of 85.7 kDa after removal of the signal peptide.The apparent molecular mass of CD26-His is 35-55 kDa due to glycosylation.

UniProt: P27487

Pathways: Peptide Hormone Metabolism, Regulation of Leukocyte Mediated Immunity