GUCY2C Protein (AA 24-430) (His tag)

Catalog No. ABIN7092686

Product Details

Target: GUCY2C (Guanylate Cyclase 2C (Heat Stable Enterotoxin Receptor) (GUCY2C))

Protein Type: Recombinant

Protein Characteristics: AA 24-430

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This GUCY2C protein is labelled with His tag.

Purpose: Recombinant human GUCY2C protein with C-terminal 6xHis tag

Specificity: GUCY2C (Ser24-Gln430) 6xHis tag

Characteristics: Extracellular Domain Protein

Purification: Purified from cell culture supernatant by affinity chromatography

Purity: The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Storage: -20 °C,-80 °C

Storage Comment: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Expiry Date: 12 months

Target Details

Target: GUCY2C (Guanylate Cyclase 2C (Heat Stable Enterotoxin Receptor) (GUCY2C))

Alternative Name: GUCY2C (GUCY2C Products)

Synonyms: DIAR6 Protein, GUC2C Protein, MECIL Protein, MUCIL Protein, STAR Protein, AI893437 Protein, GC-C Protein, Gcc Protein, GCC Protein, gucy2c-A Protein, GUCY2C Protein, Gucy2c Protein, guanylate cyclase 2C Protein, guanylate cyclase 2c Protein, guanylate cyclase 2C L homeolog Protein, GUCY2C Protein, Gucy2c Protein, gucy2c.L Protein, gucy2c Protein

Background: This gene encodes a transmembrane protein that functions as a receptor for endogenous peptides guanylin and uroguanylin, and the heat-stable E. coli enterotoxin. The encoded protein activates the cystic fibrosis transmembrane conductance regulator. Mutations in this gene are associated with familial diarrhea (autosomal dominant) and meconium ileus (autosomal recessive). [provided by RefSeq, Nov 2016]

Molecular Weight: predicted molecular mass of 46.8 kDa after removal of the signal peptide. The apparent molecular mass of GUCY2C-His is 55-130 kDa due to glycosylation.

UniProt: P25092