FOLR1 Protein (AA 25-234) (His tag)

Catalog No. ABIN7092684

Product Details

Target: FOLR1 (Folate Receptor 1 (Adult) (FOLR1))

Protein Type: Recombinant

Protein Characteristics: AA 25-234

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This FOLR1 protein is labelled with His tag.

Purpose: Recombinant Human FOLR1 Protein with C-terminal 6xHis tag

Specificity: FOLR1 (Arg25-Ser234) 6xHis tag

Characteristics: Extracellular Domain Protein

Purification: Purified from cell culture supernatant by affinity chromatography

Purity: The purity of the protein is greater than 90 % as determined by SDS-PAGE and Coomassie blue staining.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Storage: -20 °C,-80 °C

Storage Comment: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Expiry Date: 12 months

Target Details

Target: FOLR1 (Folate Receptor 1 (Adult) (FOLR1))

Alternative Name: FOLR1 (FOLR1 Products)

Synonyms: FBP Protein, FOLR Protein, fbp Protein, folr Protein, folr1 Protein, FBP1 Protein, Folbp-1 Protein, Folbp1 Protein, Fbp1 Protein, FOLR1 Protein, Folr1 Protein, folate receptor 1 Protein, folate receptor 1 (adult) Protein, folate receptor 1 (adult) L homeolog Protein, zgc:165502 Protein, Folate receptor alpha Protein, folate receptor alpha Protein, FOLR1 Protein, folr1 Protein, folr1.L Protein, zgc:165502 Protein, Folr1 Protein, LOC100066084 Protein, LOC100725439 Protein

Background: The protein encoded by this gene is a member of the folate receptor family. Members of this gene family bind folic acid and its reduced derivatives, and transport 5-methyltetrahydrofolate into cells. This gene product is a secreted protein that either anchors to membranes via a glycosyl-phosphatidylinositol linkage or exists in a soluble form. Mutations in this gene have been associated with neurodegeneration due to cerebral folate transport deficiency. Due to the presence of two promoters, multiple transcription start sites, and alternative splicing, multiple transcript variants encoding the same protein have been found for this gene.

Molecular Weight: predicted molecular mass of 25.5 kDa after removal of the signal peptide.

Gene ID: 2348

UniProt: P15328

Pathways: Dicarboxylic Acid Transport