DCC Protein (AA 32-1097) (Fc Tag)
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- Target See all DCC Proteins
- DCC (Deleted in Colorectal Carcinoma (DCC))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 32-1097
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This DCC protein is labelled with Fc Tag.
- Characteristics
- Human Netrin receptor DCC / DCC Protein, Fc Tag (MALS verified)
- Purity
- >90 % as determined by SDS-PAGE.
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product DCC Protein
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- Application Notes
- MALS verified
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- 50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH 7.5
- Storage
- -20 °C
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- Target
- DCC (Deleted in Colorectal Carcinoma (DCC))
- Alternative Name
- Netrin receptor DCC (DCC Products)
- Synonyms
- CRC18 Protein, CRCR1 Protein, IGDCC1 Protein, MRMV1 Protein, DCC Protein, zdcc Protein, C030036D22Rik Protein, Igdcc1 Protein, xdcc Protein, XDCCa Protein, dcca-A Protein, Dcc Protein, DCC netrin 1 receptor Protein, deleted in colorectal carcinoma Protein, netrin receptor DCC Protein, DCC Protein, dcc Protein, Dcc Protein, LOC100712666 Protein
- Background
- Receptor for netrin required for axon guidance. Mediates axon attraction of neuronal growth cones in the developing nervous system upon ligand binding. Its association with UNC5 proteins may trigger signaling for axon repulsion. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand. Implicated as a tumor suppressor gene.
- Molecular Weight
- 144.1 kDa
- NCBI Accession
- NP_005206
- Pathways
- Regulation of Cell Size
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