Tissue factor Protein (AA 33-251) (Fc Tag)
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- Target See all Tissue factor (F3) Proteins
- Tissue factor (F3) (Coagulation Factor III (thromboplastin, Tissue Factor) (F3))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 33-251
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This Tissue factor protein is labelled with Fc Tag.
- Characteristics
- Human Coagulation Factor III / Tissue Factor Protein, Fc Tag
- Purity
- >95 % as determined by SDS-PAGE.
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product F3 Protein
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Coagulation Factor III (thromboplastin, Tissue Factor) (F3) (AA 33-251) protein (His tag)
F3 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Coagulation Factor III (thromboplastin, Tissue Factor) (F3) (AA 35-248) protein (His tag)F3 Origin: Dog Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Coagulation Factor III (thromboplastin, Tissue Factor) (F3) (AA 31-251) protein (His tag)F3 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Coagulation Factor III (thromboplastin, Tissue Factor) (F3) (AA 45-154) protein (GST tag)F3 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Coagulation Factor III (thromboplastin, Tissue Factor) (F3) protein (His tag)F3 Origin: Mouse Host: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Coagulation Factor III (thromboplastin, Tissue Factor) (F3) protein (His tag)F3 Origin: Rat Host: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE
Coagulation Factor III (thromboplastin, Tissue Factor) (F3) (Active) protein (His tag)F3 Origin: Mouse Host: HEK-293 Cells Recombinant > 98 % as determined by SDS-PAGE Active
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- 50 mM Tris, 150 mM NaCl, pH 7.5
- Storage
- -20 °C
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- Target
- Tissue factor (F3) (Coagulation Factor III (thromboplastin, Tissue Factor) (F3))
- Alternative Name
- Coagulation Factor III (F3 Products)
- Synonyms
- CD142 Protein, TF Protein, TFA Protein, PRO1557 Protein, PRO2086 Protein, TFQTL1 Protein, f3 Protein, AA409063 Protein, Cf-3 Protein, Cf3 Protein, tf Protein, zgc:112151 Protein, coagulation factor III, tissue factor Protein, transferrin Protein, coagulation factor IIIa Protein, coagulation factor III Protein, tissue factor Protein, coagulation factor IIIb Protein, coagulation factor III (thromboplastin, tissue factor) S homeolog Protein, F3 Protein, TF Protein, f3a Protein, tf Protein, f3b Protein, f3.S Protein
- Background
- Full-length tissue factor (TF) is a transmembrane receptor and cofactor for factor (F)VII/FVIIa. In addition to full-length TF, an alternative spliced (as) form of TF can be generated that lacks the transmembrane domain and is released fromcells. In contrast to TF, asTF has low procoagulant activity because it lacks the transmembrane domain. Tissue factor is expressed by cells around blood vessels, such as adventitial fibroblasts, and body surfaces, such as epithelial cells, and plays a critical role in hemostasis. TF also contributes to various forms of thrombosis. Many cancers, particularly adenocarcinomas, express high levels of TF. A high level of tumor TF expression is associated with poor prognosis in many types of cancers, including breast, prostate, colorectal, and pancreatic cancer.
- Molecular Weight
- 51.2 kDa
- NCBI Accession
- NP_001984
- Pathways
- Positive Regulation of Endopeptidase Activity, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling
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