LGR4 Protein (AA 25-544) (His tag)

Catalog No. ABIN7013660

Product Details

Target: LGR4 (Leucine-Rich Repeat Containing G Protein-Coupled Receptor 4 (LGR4))

Protein Type: Recombinant

Biological Activity: Active

Protein Characteristics: AA 25-544

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This LGR4 protein is labelled with His tag.

Characteristics: Human LGR4 / GPR48 protein, His Tag

Purity: >85 % as determined by SDS-PAGE.

Endotoxin Level: Less than 1.0 EU per μg by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: PBS, pH 7.4

Storage: -20 °C

Target Details

Target: LGR4 (Leucine-Rich Repeat Containing G Protein-Coupled Receptor 4 (LGR4))

Alternative Name: LGR4 (LGR4 Products)

Synonyms: BNMD17 Protein, GPR48 Protein, 9130225G07 Protein, A330106J01Rik Protein, A930009A08Rik Protein, Gpr48 Protein, leucine rich repeat containing G protein-coupled receptor 4 Protein, leucine-rich repeat-containing G protein-coupled receptor 4 Protein, LGR4 Protein, Lgr4 Protein

Background: The fourth member of the leucine-rich repeat-containing GPCR family (LGR4, frequently referred to as GPR48) together with its family members LGR5 and -6, bind to R-spondins (RSPOs)-1-4 and result in Wnt signaling potentiation. In addition, LGR4 (as well as LGR5 and -6) is implicated in multiple cancers and promotes invasion and metastasis in colorectal, prostate, and cervical cancer cell lines.

Molecular Weight: 58.8 kDa

NCBI Accession: NP_060960