CCR5 Protein (AA 2-223, AA 227-319) (His tag,DYKDDDDK Tag)
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- Target See all CCR5 Proteins
- CCR5 (Chemokine (C-C Motif) Receptor 5 (CCR5))
- Protein Type
- Recombinant
- Biological Activity
- Active
- Protein Characteristics
- AA 2-223, AA 227-319
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This CCR5 protein is labelled with His tag,DYKDDDDK Tag.
- Characteristics
- Human CCR5 Protein, Flag,His Tag
- Purity
- >85 % as determined by SDS-PAGE.
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product CCR5 Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- 50 mM HEPES, 150 mM NaCl, DDM, CHS, pH 7.5
- Storage
- -80 °C
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- Target
- CCR5 (Chemokine (C-C Motif) Receptor 5 (CCR5))
- Alternative Name
- CCR5 (CCR5 Products)
- Synonyms
- CC-CKR-5 Protein, CCCKR5 Protein, CCR-5 Protein, CD195 Protein, CKR-5 Protein, CKR5 Protein, CMKBR5 Protein, IDDM22 Protein, Ckr5 Protein, Cmkbr5 Protein, CCR1-L Protein, GPCR Protein, CCR5 Protein, AM4-7 Protein, C-C motif chemokine receptor 5 (gene/pseudogene) Protein, chemokine (C-C motif) receptor 5 Protein, C-C motif chemokine receptor 5 Protein, CCR5 Protein, Ccr5 Protein
- Background
- Receptor for a number of inflammatory CC-chemokines including CCL3/MIP-1-alpha, CCL4/MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation.5 Publications (Microbial infection) Acts as a coreceptor (CD4 being the primary receptor) of human immunodeficiency virus-1/HIV-1.
- Molecular Weight
- 46.0 kDa
- Pathways
- Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process, Regulation of Cell Size
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