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NKG2C & CD94 (AA 94-231) (Active) protein (Fc Tag)

Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Catalog No. ABIN7013508
  • Target
    NKG2C & CD94
    Protein Type
    Recombinant
    Biological Activity
    Active
    Protein Characteristics
    AA 94-231
    Origin
    • 3
    • 1
    Human
    Source
    • 4
    HEK-293 Cells
    Purification tag / Conjugate
    Fc Tag
    Characteristics
    Human NKG2C&CD94 Protein, Fc Tag
    Purity
    >95 % as determined by SDS-PAGE.
    Endotoxin Level
    Less than 1.0 EU per μg by the LAL method.
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    PBS, pH 7.4
    Storage
    -20 °C
  • Target
    NKG2C & CD94
    Sub Type
    Cocktail
    Background
    CD94 plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. KLRD1 (CD94) is an antigen preferentially expressed on NK cells and is classified as a type II membrane protein because it has an external C terminus. NKG2C/CD159c is used as a receptor for NK cells and some cytotoxic T cells to recognize MHC class I HLA-E molecules. CD94 pairs with the NKG2 Molecule as a heterodimer. The CD94/NKG2 complex, on the surface of natural killer cells interacts with Human Leukocyte Antigen (HLA)-E on target cells.
    Molecular Weight
    57.1 kDa
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