MUC17 Protein (AA 4131-4390) (His tag)
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- Target See all MUC17 products
- MUC17 (Mucin 17, Cell Surface Associated (MUC17))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 4131-4390
- Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This MUC17 protein is labelled with His tag.
- Characteristics
- Human MUC-17 Protein, His Tag
- Purity
- >90 % as determined by SDS-PAGE.
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Storage
- -20 °C
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- Target
- MUC17 (Mucin 17, Cell Surface Associated (MUC17))
- Alternative Name
- MUC-17 (MUC17 Products)
- Synonyms
- MUC3 Protein, mucin 17, cell surface associated Protein, MUC17 Protein
- Background
- Membrane mucins have several functions in epithelial cells including cytoprotection, extravasation during metastases, maintenance of luminal structure, and signal transduction. MUC17, contains an extended, repetitive extracellular glycosylation domain and a carboxyl terminus with two EGF-like domains, a SEA module domain, a transmembrane domain, and a cytoplasmic domain with potential serine and tyrosine phosphorylation sites. Interacts via its C-terminus with PDZK1 and this interaction appears important for proper localization. Probably plays a role in maintaining homeostasis on mucosal surfaces.
- Molecular Weight
- 31.2 kDa
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