MICA Protein (AA 24-308) (Fc Tag)
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- Target See all MICA Proteins
- MICA (MHC Class I Polypeptide-Related Sequence A (MICA))
- Protein Type
- Recombinant
- Biological Activity
- Active
- Protein Characteristics
- AA 24-308
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This MICA protein is labelled with Fc Tag.
- Characteristics
- Human MICA Protein, Fc Tag (MALS verified)
- Purity
- >95 % as determined by SDS-PAGE.
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product MICA Protein
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- Application Notes
- MALS verified
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Storage
- -20 °C
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- Target
- MICA (MHC Class I Polypeptide-Related Sequence A (MICA))
- Alternative Name
- MICA (MICA Products)
- Synonyms
- MIC-A Protein, PERB11.1 Protein, MHC class I polypeptide-related sequence A Protein, MICA Protein
- Background
- MHC class I polypeptide-related sequence A (MICA) belongs to the MHC class I family and MIC subfamily. MICA contains one Ig-like C1-type (immunoglobulin-like) domain. Unlike classical MHC class I molecules, MICA does not form a heterodimer with beta-2-microglobulin. MICA acts as a stress-induced self-antigen that is recognized by gamma delta T-cells. MICA is ligand for the KLRK1/NKG2D receptor. MICA bind to KLRK1 leads to cell lysis.
- Molecular Weight
- 59.3 kDa
- Pathways
- Activation of Innate immune Response, Transition Metal Ion Homeostasis, Human Leukocyte Antigen (HLA) in Adaptive Immune Response
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