IL-33 Protein (AA 109-270) (His tag)
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- Target See all IL-33 (IL33) Proteins
- IL-33 (IL33) (Interleukin 33 (IL33))
- Protein Type
- Recombinant
- Biological Activity
- Active
- Protein Characteristics
- AA 109-270
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Origin
- Cynomolgus
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This IL-33 protein is labelled with His tag.
- Characteristics
- Cynomolgus IL-33 Protein, His Tag
- Purity
- >95 % as determined by SDS-PAGE.
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product IL33 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Storage
- -20 °C
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- Target
- IL-33 (IL33) (Interleukin 33 (IL33))
- Alternative Name
- IL-33 (IL33 Products)
- Synonyms
- IL33 Protein, C9orf26 Protein, DVS27 Protein, IL1F11 Protein, NF-HEV Protein, NFEHEV Protein, RP11-575C20.2 Protein, 9230117N10Rik Protein, Il-33 Protein, Il1f11 Protein, RGD1311155 Protein, interleukin 33 Protein, IL33 Protein, Il33 Protein
- Background
- Interleukin 33 (IL33) is known as C9orf26, DKFZp586H0523, DVS27, NF-HEV, NFEHEV, RP11-575C20.2,and is a cytokine belonging to the IL-1 superfamily. IL-33 induces helper T cells, mast cells, eosinophils and basophils to produce type 2 cytokines. IL-33 mediates its biological effects by interacting with the receptors ST2 (aka IL1RL1) and IL-1 Receptor Accessory Protein (IL1RAP), activating intracellular molecules in the NF-κB and MAP kinase signaling pathways that drive production of type 2 cytokines (e.g. IL-5 and IL-13) from polarized Th2 cells. In vivo, IL-33 induces the expression of IL-4, IL-5, and IL-13 and leads to severe pathological changes in mucosal organs.
- Molecular Weight
- 20.2 kDa
- NCBI Accession
- XP_005581824
- Pathways
- Production of Molecular Mediator of Immune Response
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