CTGF Protein (AA 27-349) (His tag)
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- Target See all CTGF Proteins
- CTGF (Connective Tissue Growth Factor (CTGF))
- Protein Type
- Recombinant
- Biological Activity
- Active
- Protein Characteristics
- AA 27-349
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Origin
- Rhesus Monkey
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This CTGF protein is labelled with His tag.
- Characteristics
- Rhesus macaque CTGF / CCN2 Protein, His Tag
- Purity
- >90 % as determined by SDS-PAGE.
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product CTGF Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- 5 mM HAC,100 mM NaCl, pH 5.5
- Storage
- -20 °C
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- Target
- CTGF (Connective Tissue Growth Factor (CTGF))
- Alternative Name
- CTGF (CTGF Products)
- Synonyms
- Ccn2 Protein, Fisp12 Protein, Hcs24 Protein, fisp-12 Protein, CCN2 Protein, HCS24 Protein, IGFBP8 Protein, NOV2 Protein, CTGRP Protein, ctgf Protein, hm:zeh1559 Protein, si:dkey-266k12.4 Protein, wu:fl25c03 Protein, zeh1559 Protein, zgc:136644 Protein, XCTGF Protein, ccn2 Protein, nov2 Protein, hcs24 Protein, igfbp8 Protein, CTGF Protein, si:ch211-173b8.2 Protein, connective tissue growth factor Protein, connective tissue growth factor a Protein, connective tissue growth factor L homeolog Protein, connective tissue growth factor b Protein, Ctgf Protein, CTGF Protein, ctgfa Protein, ctgf.L Protein, ctgf Protein, ctgfb Protein
- Background
- Connective Tissue Growth Factor (CTGF), also known as CCN2, is a member of the CCN (CCN1-6) family of modular matricellular proteins. Like other CCN proteins, mature human CTGF consists of IGF-binding protein domain, a vWF-C domain, a TSP-1 domain, and a cysteine knot heparin-binding domain. CTGF promotes proliferation and differentiation of chondrocytes. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor-induced DNA synthesis. Analysis of CCN2 function in vivo has focused primarily on its key role as a mediator of excess ECM synthesis in multiple fibrotic diseases.
- Molecular Weight
- 37.3 kDa
- Pathways
- Regulation of Lipid Metabolism by PPARalpha, Positive Regulation of Endopeptidase Activity, Growth Factor Binding
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