TACI Protein (AA 2-166, R119A, R122A) (Fc Tag)
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- Target See all TACI (TNFRSF13B) Proteins
- TACI (TNFRSF13B) (Tumor Necrosis Factor Receptor Superfamily, Member 13B (TNFRSF13B))
- Protein Type
- Recombinant
- Biological Activity
- Active
- Protein Characteristics
- AA 2-166, R119A, R122A
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This TACI protein is labelled with Fc Tag.
- Purpose
- Human TACI / TNFRSF13B (R119A, R122A) Protein, Fc Tag (MALS verified)
- Purity
- >95 % as determined by SDS-PAGE.
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product TNFRSF13B Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Storage
- -20 °C
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- Target
- TACI (TNFRSF13B) (Tumor Necrosis Factor Receptor Superfamily, Member 13B (TNFRSF13B))
- Alternative Name
- TACI (TNFRSF13B Products)
- Synonyms
- CD267 Protein, CVID Protein, CVID2 Protein, RYZN Protein, TACI Protein, TNFRSF14B Protein, TNFRSF13B Protein, 1200009E08Rik Protein, Taci Protein, TNF receptor superfamily member 13B Protein, tumor necrosis factor receptor superfamily, member 13b Protein, TNFRSF13B Protein, Tnfrsf13b Protein
- Background
- Transmembrane activator and CAML interactor (TACI), also known as tumor necrosis factor receptor superfamily member 13B (TNFRSF13B). It was originally discovered because of its ability to interact with calcium-modulator and cyclophilin ligand (CAML). TACI was later found to play a crucial role in humoral immunity by interacting with two members of the TNF family: BAFF and APRIL. The present study demonstrated that, in NSCLC, a proliferation-inducing ligand (APRIL), B-cell maturation antigen (BCMA)and transmembrane activator and CAML interactor (TACI) proteins are abnormally expressed by immunohistochemistry, reverse transcription-quantitative polymerase chain reaction and western blotting. In addition, the expression of APRIL, BCMA and TACI were observed to be involved in extracellular signal-regulated kinase (ERK)1/2 activation in A549 cells.
- Molecular Weight
- 44.8 kDa
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