PTK7 Protein (AA 31-704) (Fc Tag)
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- Target See all PTK7 Proteins
- PTK7 (PTK7 Protein tyrosine Kinase 7 (PTK7))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 31-704
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This PTK7 protein is labelled with Fc Tag.
- Purpose
- Human PTK7 / CCK4 Protein, Fc Tag (MALS verified)
- Purity
- >95 % as determined by reduced SDS-PAGE.
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product PTK7 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- 50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH 7.5
- Storage
- -20 °C
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- Target
- PTK7 (PTK7 Protein tyrosine Kinase 7 (PTK7))
- Alternative Name
- PTK7 (PTK7 Products)
- Synonyms
- PTK7 Protein, CCK-4 Protein, CCK4 Protein, Srf Protein, 8430404F20Rik Protein, chz Protein, mPTK7/CCK4 Protein, KLG Protein, protein tyrosine kinase 7 (inactive) Protein, protein tyrosine kinase 7 Protein, PTK7 protein tyrosine kinase 7 Protein, PTK7 Protein, Ptk7 Protein
- Background
- PTK7, highly expressed in lung, liver, pancreas, kidney, placenta and melanocytes. Weakly expressed in thyroid gland, ovary, brain, heart and skeletal muscle. Also expressed in erythroleukemia cells. Inactive tyrosine kinase involved in Wnt signaling pathway. Component of both the non-canonical (also known as the Wnt/planar cell polarity signaling) and the canonical Wnt signaling pathway. Functions in cell adhesion, cell migration, cell polarity, proliferation, actin cytoskeleton reorganization and apoptosis. Has a role in embryogenesis, epithelial tissue organization and angiogenesis.
- Molecular Weight
- 101.1 kDa
- NCBI Accession
- NP_002812
- Pathways
- RTK Signaling, Tube Formation
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