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KREMEN2 Protein (AA 26-364) (His tag)

KREMEN2 Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by reduced SDS-PAGE. Active
Catalog No. ABIN7013004
  • Target See all KREMEN2 Proteins
    KREMEN2 (Kringle Containing Transmembrane Protein 2 (KREMEN2))
    Protein Type
    Recombinant
    Biological Activity
    Active
    Protein Characteristics
    AA 26-364
    Origin
    • 6
    • 3
    • 1
    Human
    Source
    • 4
    • 4
    • 2
    HEK-293 Cells
    Purification tag / Conjugate
    This KREMEN2 protein is labelled with His tag.
    Purpose
    Human Kremen-2 protein, His Tag
    Purity
    >95 % as determined by reduced SDS-PAGE.
    Endotoxin Level
    Less than 1.0 EU per μg by the LAL method.
    Top Product
    Discover our top product KREMEN2 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    PBS, 0.2M Arginine, pH 7.4
    Storage
    -20 °C
  • Target
    KREMEN2 (Kringle Containing Transmembrane Protein 2 (KREMEN2))
    Alternative Name
    KREMEN2 (KREMEN2 Products)
    Synonyms
    krm2 Protein, KREMEN2 Protein, MGC147633 Protein, KRM2 Protein, 2900054E04Rik Protein, Krm2 Protein, kringle containing transmembrane protein 2 S homeolog Protein, kringle containing transmembrane protein 2 Protein, kremen2.S Protein, KREMEN2 Protein, kremen2 Protein, Kremen2 Protein
    Background
    Kremen2 (Krm2) plays an important role in embryonic development, bone formation, and tumorigenesis as a crucial regulator of classical Wnt/β-catenin signaling pathway. Krm1 and its paralog Krm2 share the ability to bind Dkk1 and inhibit Wnt signaling, both processes previously shown to rely on the extracellular domain. Previous studies have shown that Krm2 may be involved in embryonic development, bone formation, neural ridge formation and tumorigenesis and could be a biomarker of grading and a potential therapeutic target in gastric cancer.
    Molecular Weight
    38.0 kDa
    Pathways
    WNT Signaling
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