FGF19 Protein (AA 25-216) (Fc Tag)
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- Target See all FGF19 Proteins
- FGF19 (Fibroblast Growth Factor 19 (FGF19))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 25-216
- Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This FGF19 protein is labelled with Fc Tag.
- Purpose
- Human FGF19 Protein, Fc Tag
- Purity
- >90 % as determined by SDS-PAGE.
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product FGF19 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- 50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH 7.5
- Storage
- -20 °C
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- Target
- FGF19 (Fibroblast Growth Factor 19 (FGF19))
- Alternative Name
- FGF19 (FGF19 Products)
- Synonyms
- FGF-19 Protein, Fgf15 Protein, fibroblast growth factor 19 Protein, FGF19 Protein, Fgf19 Protein, fgf19 Protein
- Background
- Fibroblast growth factor (FGF)19 is the first members of a new subfamily of FGFs and could act as hormones. During fetal life, FGF15/19 is involved in organogenesis, affecting the development of the ear, eye, heart, and brain. FGFs-FGFRs are involved in regulation of many biological processes such as embryonic development, cell proliferation, differentiation, and tissue repair. The dysregulation of FGF-FGFR was observed in different types of diseases, disorders, and cancers. Notably, aberrant expression of FGF19/FGFR4 contributes to Hepatocellular Carcinoma progression.
- Molecular Weight
- 47.9 kDa
- Pathways
- RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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