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MR1 Protein (Fc Tag)

MR1 Origin: Human Host: HEK-293 Cells Recombinant
Catalog No. ABIN6964404
  • Target See all MR1 Proteins
    MR1 (Major Histocompatibility Complex, Class I-Related (MR1))
    Protein Type
    Recombinant
    Origin
    • 4
    • 2
    • 1
    • 1
    • 1
    Human
    Source
    • 4
    • 3
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This MR1 protein is labelled with Fc Tag.
    Sequence
    MR1 (R23-Met302)+hFc(GLU99-ALA330)
    Characteristics
    Tagged Protein: C-Human Fc tag
    Purification
    affinity purification
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    Discover our top product MR1 Protein
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Reconstitute with deionized water
    Buffer
    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    Preservative
    Without preservative
    Storage
    -80 °C
    Storage Comment
    Store at -80°C for 12 months (Avoid repeated freezing and thawing)
    Expiry Date
    12 months
  • Target
    MR1 (Major Histocompatibility Complex, Class I-Related (MR1))
    Alternative Name
    MR1 (MR1 Products)
    Synonyms
    YFV Protein, hlals Protein, MGC154362 Protein, MR1 Protein, DKFZp468C1823 Protein, HLALS Protein, H2ls Protein, Hlals Protein, MHC class I antigen YF5 Protein, major histocompatibility complex, class I-related Protein, major histocompatibility complex, class I-related L homeolog Protein, YF5 Protein, MR1 Protein, mr1.L Protein, mr1 Protein, Mr1 Protein
    Background
    Synonymes: HLALS
    Description: MAIT (mucosal-associated invariant T-cells) lymphocytes represent a small population of T-cells primarily found in the gut. The protein encoded by this gene is an antigen-presenting molecule that presents metabolites of microbial vitamin B to MAITs. This presentation may activate the MAITs to regulate the amounts of specific types of bacteria in the gut. Several transcript variants encoding different isoforms have been found for this gene, and a pseudogene of it has been detected about 36 kbp upstream on the same chromosome. [provided by RefSeq, Jul 2015]
    Molecular Weight
    56.32 kDa
    UniProt
    Q95460
    Pathways
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
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