CGRP Protein (AA 85-141) (Fc Tag)

Catalog No. ABIN6964348

Product Details

Target: CGRP (CALCA) (Calcitonin-Related Polypeptide alpha (CALCA))

Protein Type: Recombinant

Protein Characteristics: AA 85-141

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This CGRP protein is labelled with Fc Tag.

Purpose: Recombinant Human CALCA(85-141) Protein with C-terminal human Fc tag

Sequence: TGFB2 (Ala26-Ser82)+hFc (Glu99-Ala330)

Specificity: CALCA (Cys85-Asn141) hFc (Glu99-Ala330)

Characteristics: Extracellular Domain Protein

Purification: Purified from cell culture supernatant by affinity chromatography

Purity: The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Storage: -20 °C,-80 °C

Storage Comment: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Expiry Date: 12 months

Target Details

Target: CGRP (CALCA) (Calcitonin-Related Polypeptide alpha (CALCA))

Alternative Name: CALCA (CALCA Products)

Synonyms: CALC1 Protein, CGRP Protein, CGRP-I Protein, CGRP1 Protein, CT Protein, KC Protein, CALC Protein, CALCA Protein, CALC3 Protein, ci-ct Protein, calca Protein, CA Protein, CGRP-1 Protein, Calc Protein, Calc1 Protein, Cgrp Protein, Ct Protein, Ctn Protein, calcitonin Protein, CAL6 Protein, Cal1 Protein, RATCAL6 Protein, CGRPI Protein, calc Protein, cgrp Protein, zgc:92886 Protein, calcitonin related polypeptide alpha Protein, calcitonin related polypeptide beta Protein, calcitonin-related polypeptide alpha Protein, calcitonin Protein, calcitonin/calcitonin-related polypeptide, alpha Protein, calcitonin-related polypeptide beta Protein, calcitonin gene-related peptide 2 Protein, CALCA Protein, CALCB Protein, ci-ct Protein, calca Protein, Calca Protein, LOC100008771 Protein

Background: This gene encodes the peptide hormones calcitonin, calcitonin gene-related peptide and katacalcin by tissue-specific alternative RNA splicing of the gene transcripts and cleavage of inactive precursor proteins. Calcitonin is involved in calcium regulation and acts to regulate phosphorus metabolism. Calcitonin gene-related peptide functions as a vasodilator and as an antimicrobial peptide while katacalcin is a calcium-lowering peptide. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Aug 2014]

Molecular Weight: predicted molecular mass of 32.4 kDa after removal of the signal peptide. The apparent molecular mass of CALCA(85-141)-hFc is 35-55 kDa due to glycosylation.

UniProt: P01258

Pathways: Hormone Activity, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Skeletal Muscle Fiber Development, Feeding Behaviour