RHOC Protein (AA 1-190) (Fc Tag)
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- Target See all RHOC Proteins
- RHOC (Ras Homolog Gene Family, Member C (RHOC))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-190
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This RHOC protein is labelled with Fc Tag.
- Purpose
- Recombinant Human RHOC Protein with C-terminal human Fc tag
- Specificity
- RHOC (Met1-Cys190) hFc (Glu99-Ala330)
- Characteristics
- Extracellular Domain Protein
- Purification
- Purified from cell culture supernatant by affinity chromatography
- Purity
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
- Top Product
- Discover our top product RHOC Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- RHOC (Ras Homolog Gene Family, Member C (RHOC))
- Alternative Name
- RhoC (RHOC Products)
- Synonyms
- ARHC Protein, LOC100221682 Protein, ARH9 Protein, H9 Protein, RHOH9 Protein, AI324259 Protein, Arh9 Protein, Arhc Protein, CRHOC Protein, ras homolog family member C L homeolog Protein, ras homolog family member C Protein, rhoc.L Protein, RHOC Protein, rhoc Protein, Rhoc Protein
- Background
- This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The protein encoded by this gene is prenylated at its C-terminus, and localizes to the cytoplasm and plasma membrane. It is thought to be important in cell locomotion. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]
- Molecular Weight
- predicted molecular mass of 47.8 kDa after removal of the signal peptide. The apparent molecular mass of RHOC-hFc is 35-55 kDa due to glycosylation.
- UniProt
- P08134
- Pathways
- WNT Signaling, Cell-Cell Junction Organization
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