PTGER4 Protein (AA 1-19) (Fc Tag)
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- Target See all PTGER4 Proteins
- PTGER4 (Prostaglandin E Receptor 4 (Subtype EP4) (PTGER4))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-19
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This PTGER4 protein is labelled with Fc Tag.
- Purpose
- Recombinant Human PTGER4 Protein with C-terminal human Fc tag
- Specificity
- PTGER4 (Met1-Ser19) hFc (Glu99-Ala330)
- Characteristics
- Extracellular Domain Protein
- Purification
- Purified from cell culture supernatant by affinity chromatography
- Purity
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
- Top Product
- Discover our top product PTGER4 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- PTGER4 (Prostaglandin E Receptor 4 (Subtype EP4) (PTGER4))
- Alternative Name
- PTGER4 (PTGER4 Products)
- Synonyms
- EP4 Protein, PGE2R-EP4 Protein, ptger4 Protein, ptger4l Protein, PTGER4 Protein, EP4R Protein, Ptgerep4 Protein, Ptger Protein, ep4 Protein, prostaglandin E receptor 4 Protein, prostaglandin E receptor 4 (subtype EP4) Protein, prostaglandin E receptor 4 (subtype EP4) a Protein, prostaglandin E receptor 4 subtype EP4 Protein, PTGER4 Protein, ptger4a Protein, ptger4 Protein, Ptger4 Protein
- Background
- The protein encoded by this gene is a member of the G-protein coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). This receptor can activate T-cell factor signaling. It has been shown to mediate PGE2 induced expression of early growth response 1 (EGR1), regulate the level and stability of cyclooxygenase-2 mRNA, and lead to the phosphorylation of glycogen synthase kinase-3. Knockout studies in mice suggest that this receptor may be involved in the neonatal adaptation of circulatory system, osteoporosis, as well as initiation of skin immune responses. [provided by RefSeq, Jul 2008]
- Molecular Weight
- predicted molecular mass of 28.1 kDa after removal of the signal peptide. The apparent molecular mass of PTGER4-hFc is 35-55 kDa due to glycosylation.
- UniProt
- P35408
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