IFNGR2 Protein (AA 28-247) (Fc Tag)
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- Target See all IFNGR2 Proteins
- IFNGR2 (Interferon gamma Receptor 2 (Interferon gamma Transducer 1) (IFNGR2))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 28-247
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This IFNGR2 protein is labelled with Fc Tag.
- Purpose
- Recombinant human IFNGR2 protein with C-terminal human Fc tag
- Specificity
- IFNGR2 (Ser28-Gln247) hFc (Glu99-Ala330)
- Characteristics
- Extracellular Domain Protein
- Purification
- Purified from cell culture supernatant by affinity chromatography
- Purity
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- IFNGR2 (Interferon gamma Receptor 2 (Interferon gamma Transducer 1) (IFNGR2))
- Alternative Name
- IFNGR2 (IFNGR2 Products)
- Synonyms
- Ifgr2 Protein, Ifgt Protein, AF-1 Protein, IFGR2 Protein, IFNGT1 Protein, interferon gamma receptor 2 Protein, Ifngr2 Protein, IFNGR2 Protein, LOC487739 Protein
- Background
- This gene (IFNGR2) encodes the non-ligand-binding beta chain of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. Defects in IFNGR2 are a cause of mendelian susceptibility to mycobacterial disease (MSMD), also known as familial disseminated atypical mycobacterial infection. MSMD is a genetically heterogeneous disease with autosomal recessive, autosomal dominant or X-linked inheritance. [provided by RefSeq, Jul 2008]
- Molecular Weight
- predicted molecular mass of 51.0 kDa after removal of the signal peptide. The apparent molecular mass of IFNGR2-hFc is 55-70 kDa due to glycosylation.
- UniProt
- P38484
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