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IFNAR2 Protein (AA 27-243) (Fc Tag)

IFNAR2 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Catalog No. ABIN6964274
  • Target See all IFNAR2 Proteins
    IFNAR2 (Interferon alpha/beta Receptor 2 (IFNAR2))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 27-243
    Origin
    • 10
    • 2
    • 1
    • 1
    Human
    Source
    • 6
    • 3
    • 2
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This IFNAR2 protein is labelled with Fc Tag.
    Purpose
    Recombinant human IFNAR2 protein with C-terminal human Fc tag
    Specificity
    IFNAR2 (Ile27-Lys243) hFc (Glu99-Ala330)
    Characteristics
    Extracellular Domain Protein
    Purification
    Purified from cell culture supernatant by affinity chromatography
    Purity
    The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    Expiry Date
    12 months
  • Target
    IFNAR2 (Interferon alpha/beta Receptor 2 (IFNAR2))
    Alternative Name
    IFNAR2 (IFNAR2 Products)
    Synonyms
    AI747302 Protein, Ifnar-2 Protein, IFN-R Protein, IFN-alpha-REC Protein, IFNABR Protein, IFNARB Protein, IFN-R-2 Protein, IFNBR Protein, interferon alpha and beta receptor subunit 2 Protein, interferon (alpha and beta) receptor 2 Protein, IFNAR2 Protein, Ifnar2 Protein
    Background
    The protein encoded by this gene is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. The protein belongs to the type II cytokine receptor family. Mutations in this gene are associated with Immunodeficiency 45. [provided by RefSeq, Jul 2020]
    Molecular Weight
    predicted molecular mass of 50.9 kDa after removal of the signal peptide. The apparent molecular mass of IFNAR2-hFc is 55-70 kDa due to glycosylation.
    UniProt
    P48551
    Pathways
    JAK-STAT Signaling, Hepatitis C
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