IFNAR1 Protein (AA 28-436) (His tag)
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- Target See all IFNAR1 Proteins
- IFNAR1 (Interferon alpha/beta Receptor 1 (IFNAR1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 28-436
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This IFNAR1 protein is labelled with His tag.
- Purpose
- Recombinant Human IFNAR1 Protein with C-terminal 6xHis tag
- Specificity
- IFNAR1 (Lys28-Lys436) 6xHis Tag
- Characteristics
- Extracellular Domain Protein
- Purification
- Purified from cell culture supernatant by affinity chromatography
- Purity
- The purity of the protein is greater than 90 % as determined by SDS-PAGE and Coomassie blue staining.
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- IFNAR1 (Interferon alpha/beta Receptor 1 (IFNAR1))
- Alternative Name
- IFNAR1 (IFNAR1 Products)
- Synonyms
- ifnar1 Protein, IFNAR1 Protein, CD118 Protein, Ifar Protein, Ifnar Protein, Ifrc Protein, Infar Protein, AVP Protein, IFN-alpha-REC Protein, IFNAR Protein, IFNBR Protein, IFRC Protein, IFN-R-1 Protein, interferon alpha and beta receptor subunit 1 Protein, interferon-alpha/beta receptor alpha chain-like Protein, interferon (alpha and beta) receptor 1 Protein, interferon alpha/beta receptor 1 Protein, IFNAR1 Protein, ifnar1 Protein, Ifnar1 Protein, LOC609830 Protein
- Background
- The protein encoded by this gene is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. The protein belongs to the type II cytokine receptor family and functions as an antiviral factor. [provided by RefSeq, Jul 2020]
- Molecular Weight
- predicted molecular mass of 48.0 kDa after removal of the signal peptide.The apparent molecular mass of IFNAR1-His is 70-100 kDa due to glycosylation.
- UniProt
- P17181
- Pathways
- JAK-STAT Signaling, Hepatitis C
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