BRD4 Protein (AA 1-1362) (Fc Tag)

Catalog No. ABIN6964231

Product Details

Target: BRD4 (Bromodomain Containing 4 (BRD4))

Protein Type: Recombinant

Protein Characteristics: AA 1-1362

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This BRD4 protein is labelled with Fc Tag.

Purpose: Recombinant human BRD4 protein with C-terminal human Fc tag

Specificity: BRD4 (Met1-Phe1362) hFc (Glu99-Ala330)

Characteristics: Extracellular Domain Protein

Purification: Purified from cell culture supernatant by affinity chromatography

Purity: The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Storage: -20 °C,-80 °C

Storage Comment: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Expiry Date: 12 months

Target Details

Target: BRD4 (Bromodomain Containing 4 (BRD4))

Alternative Name: BRD4 (BRD4 Products)

Synonyms: brd4-b Protein, BRD4 Protein, fb18g03 Protein, wu:fb18g03 Protein, CAP Protein, HUNK1 Protein, HUNKI Protein, MCAP Protein, Brd5 Protein, WI-11513 Protein, bromodomain containing 4 L homeolog Protein, bromodomain containing 4 Protein, bromodomain-containing protein 4 Protein, brd4.L Protein, BRD4 Protein, brd4 Protein, LOC100409351 Protein, Brd4 Protein

Background: The protein encoded by this gene is homologous to the murine protein MCAP, which associates with chromosomes during mitosis, and to the human RING3 protein, a serine/threonine kinase. Each of these proteins contains two bromodomains, a conserved sequence motif which may be involved in chromatin targeting. This gene has been implicated as the chromosome 19 target of translocation t(15,19)(q13,p13.1), which defines an upper respiratory tract carcinoma in young people. Two alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2008]

Molecular Weight: predicted molecular mass of 178.4 kDa after removal of the signal peptide.

UniProt: O60885

Pathways: Chromatin Binding, SARS-CoV-2 Protein Interactome