PVRL4 Protein (AA 32-349) (His tag)
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- Target See all PVRL4 Proteins
- PVRL4 (Poliovirus Receptor-Related 4 (PVRL4))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 32-349
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This PVRL4 protein is labelled with His tag.
- Purpose
- Recombinant human NECTIN-4 protein with C-terminal 6xHis tag
- Specificity
- NECTIN-4 (Gly32-Ser349) 6xHis Tag
- Characteristics
- Extracellular Domain Protein
- Purification
- Purified from cell culture supernatant by affinity chromatography
- Purity
- The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
- Top Product
- Discover our top product PVRL4 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- PVRL4 (Poliovirus Receptor-Related 4 (PVRL4))
- Alternative Name
- Nectin-4 (PVRL4 Products)
- Synonyms
- PVRL4 Protein, si:ch211-155e24.1 Protein, 1200017F15Rik Protein, Prr4 Protein, RGD1559826 Protein, EDSS1 Protein, LNIR Protein, PRR4 Protein, nectin-4 Protein, nectin cell adhesion molecule 4 Protein, NECTIN4 Protein, nectin4 Protein, Nectin4 Protein
- Background
- This gene encodes a member of the nectin family. The encoded protein contains two immunoglobulin-like (Ig-like) C2-type domains and one Ig-like V-type domain. It is involved in cell adhesion through trans-homophilic and -heterophilic interactions. It is a single-pass type I membrane protein. The soluble form is produced by proteolytic cleavage at the cell surface by the metalloproteinase ADAM17/TACE. The secreted form is found in both breast tumor cell lines and breast tumor patients. Mutations in this gene are the cause of ectodermal dysplasia-syndactyly syndrome type 1, an autosomal recessive disorder. Alternatively spliced transcript variants have been found but the full-length nature of the variant has not been determined.[provided by RefSeq, Jan 2011]
- Molecular Weight
- predicted molecular mass of 34.9 kDa after removal of the signal peptide.The apparent molecular mass of NECTIN-4-His is 35-55 kDa due to glycosylation.
- UniProt
- Q96NY8
- Pathways
- Cell-Cell Junction Organization
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