GNRHR Protein (AA 1-38) (Fc Tag)
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- Target See all GNRHR Proteins
- GNRHR (Gonadotropin-Releasing Hormone Receptor (GNRHR))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-38
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This GNRHR protein is labelled with Fc Tag.
- Purpose
- Recombinant Human GNRHR Protein with C-terminal human Fc tag
- Specificity
- GNRHR (Met1-Arg38) hFc (Glu99-Ala330)
- Characteristics
- Extracellular Domain Protein
- Purification
- Purified from cell culture supernatant by affinity chromatography
- Purity
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
- Top Product
- Discover our top product GNRHR Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- GNRHR (Gonadotropin-Releasing Hormone Receptor (GNRHR))
- Alternative Name
- GNRHR (GNRHR Products)
- Synonyms
- GNRHR1 Protein, GRHR Protein, HH7 Protein, LHRHR Protein, LRHR Protein, GNRHR Protein, GH1 Protein, Lhrhr Protein, GNRHR1/III Protein, GNRHR2 Protein, xgnrhr Protein, gnrhr3/ii Protein, gnrh-r Protein, gonadotropin releasing hormone receptor Protein, gonadotropin-releasing hormone receptor Protein, GNRHR Protein, Gnrhr Protein, gnrhr Protein, gnrh-r Protein
- Background
- This gene encodes the receptor for type 1 gonadotropin-releasing hormone. This receptor is a member of the seven-transmembrane, G-protein coupled receptor (GPCR) family. It is expressed on the surface of pituitary gonadotrope cells as well as lymphocytes, breast, ovary, and prostate. Following binding of gonadotropin-releasing hormone, the receptor associates with G-proteins that activate a phosphatidylinositol-calcium second messenger system. Activation of the receptor ultimately causes the release of gonadotropic luteinizing hormone (LH) and follicle stimulating hormone (FSH). Defects in this gene are a cause of hypogonadotropic hypogonadism (HH). Alternative splicing results in multiple transcript variants encoding different isoforms. More than 18 transcription initiation sites in the 5' region and multiple polyA signals in the 3' region have been identified for this gene. [provided by RefSeq, Jul 2008]
- Molecular Weight
- predicted molecular mass of 30.2 kDa after removal of the signal peptide.The apparent molecular mass of GNRHR-hFc is 35-55 kDa due to glycosylation.
- UniProt
- P30968
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