IL7R Protein (AA 21-236) (Fc Tag)
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- Target See all IL7R Proteins
- IL7R (Interleukin 7 Receptor (IL7R))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 21-236
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This IL7R protein is labelled with Fc Tag.
- Purpose
- Recombinant Human IL7RA with C-terminal human Fc tag
- Specificity
- IL7RA (Glu21-Gly236) hFc (Glu99-Ala330)
- Characteristics
- Extracellular Domain Protein
- Purification
- Purified from cell culture supernatant by affinity chromatography
- Purity
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
- Top Product
- Discover our top product IL7R Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- IL7R (Interleukin 7 Receptor (IL7R))
- Alternative Name
- IL7RA (IL7R Products)
- Synonyms
- IL7R Protein, CD127 Protein, IL-7Ralpha Protein, CDW127 Protein, IL-7R-alpha Protein, IL7RA Protein, ILRA Protein, IL-7RA Protein, interleukin 7 receptor Protein, IL7R Protein, Il7r Protein
- Background
- The protein encoded by this gene is a receptor for interleukin 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukins 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in V(D)J recombination during lymphocyte development. Defects in this gene may be associated with severe combined immunodeficiency (SCID). Alternatively spliced transcript variants have been found. [provided by RefSeq, Dec 2015]
- Molecular Weight
- predicted molecular mass of 51.0 kDa after removal of the signal peptide.The apparent molecular mass of IL7RA-hFc is 55-100 kDa due to glycosylation.
- UniProt
- P16871
- Pathways
- JAK-STAT Signaling, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Regulation of Cell Size
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