HLA-A Protein (Fc Tag)

Catalog No. ABIN6964124

Product Details

Target: HLA-A (Major Histocompatibility Complex, Class I, A (HLA-A))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This HLA-A protein is labelled with Fc Tag.

Sequence: HLA-A(Gly25-Ile308)+hFc(Glu99-Ala330)

Characteristics: Tagged Protein: C-Human Fc tag

Purification: affinity purification

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstitute with deionized water

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Preservative: Without preservative

Storage: -80 °C

Storage Comment: Store at -80°C for 12 months (Avoid repeated freezing and thawing)

Expiry Date: 12 months

Target Details

Target: HLA-A (Major Histocompatibility Complex, Class I, A (HLA-A))

Alternative Name: HLA-A (HLA-A Products)

Synonyms: HLAA Protein, major histocompatibility complex, class I, A Protein, HLA-A Protein

Background: Synonymes: Aw-33, Aw-74, HLAA
Description: HLA-A belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa

Molecular Weight: 56.76 kDa

UniProt: P04439

Pathways: TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints, Human Leukocyte Antigen (HLA) in Adaptive Immune Response