CD160 Protein (CD160) (AA 27-159) (His tag)

Catalog No. ABIN6964114

Product Details

Target: CD160

Protein Type: Recombinant

Protein Characteristics: AA 27-159

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This CD160 protein is labelled with His tag.

Purpose: Recombinant human CD160 protein with C-terminal 6xHis tag

Specificity: CD160 (Ile27-Ser159) 6xHis tag

Characteristics: Extracellular Domain Protein

Purification: Purified from cell culture supernatant by affinity chromatography

Purity: The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Storage: -20 °C,-80 °C

Storage Comment: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Expiry Date: 12 months

Target Details

Target: CD160

Alternative Name: CD160 (CD160 Products)

Synonyms: CD160 Protein, RGD1563598 Protein, BY55 Protein, AU045688 Protein, By55 Protein, NK1 Protein, NK28 Protein, CD160 molecule Protein, CD160 antigen Protein, CD160 Protein, Cd160 Protein

Background: CD160 is an 27 kDa glycoprotein which was initially identified with the monoclonal antibody BY55. Its expression is tightly associated with peripheral blood NK cells and CD8 T lymphocytes with cytolytic effector activity. The cDNA sequence of CD160 predicts a cysteine-rich, glycosylphosphatidylinositol-anchored protein of 181 amino acids with a single Ig-like domain weakly homologous to KIR2DL4 Molecule. CD160 is expressed at the cell surface as a tightly disulfide-linked multimer. RNA blot analysis revealed CD160 mRNAs of 1.5 and 1.6 kb whose expression was highly restricted to circulating NK and T cells, spleen and small intestine. Within NK cells CD160 is expressed by CD56dimCD16 cells whereas among circulating T cells its expression is mainly restricted to TCRgd bearing cells and to TCRab CD8brightCD95 CD56 CD28-CD27-cells. In tissues, CD160 is expressed on all intestinal intraepithelial lymphocytes. CD160 shows a broad specificity for binding to both classical and nonclassical MHC class I molecules. [provided by RefSeq, Jul 2008]

Molecular Weight: predicted molecular mass of 15.6 kDa after removal of the signal peptide.The apparent molecular mass of CD160-His is 15-25 kDa due to glycosylation.

Gene ID: 11126

UniProt: O95971