LAG3 Protein (AA 23-245) (Fc Tag)
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- Target See all LAG3 Proteins
- LAG3 (Lymphocyte-Activation Gene 3 (LAG3))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 23-245
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This LAG3 protein is labelled with Fc Tag.
- Purpose
- Recombinant human LAG3 Protein with C-terminal Human Fc tag
- Specificity
- LAG3 (Leu23-Leu245) hFc (Glu99-Ala330)
- Characteristics
- Extracellular Domain Protein
- Purification
- Purified from cell culture supernatant by affinity chromatography
- Purity
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
- Top Product
- Discover our top product LAG3 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- LAG3 (Lymphocyte-Activation Gene 3 (LAG3))
- Alternative Name
- LAG3 (LAG3 Products)
- Synonyms
- CD223 Protein, LAG-3 Protein, Ly66 Protein, lymphocyte activating 3 Protein, lymphocyte-activation gene 3 Protein, LAG3 Protein, Lag3 Protein
- Background
- Lymphocyte-activation protein 3 belongs to Ig superfamily and contains 4 extracellular Ig-like domains. The LAG3 gene contains 8 exons. The sequence data, exon/intron organization, and chromosomal localization all indicate a close relationship of LAG3 to CD4. [provided by RefSeq, Jul 2008]
- Molecular Weight
- predicted molecular mass of 72.3 kDa after removal of the signal peptide.The apparent molecular mass of LAG3-hFc is 100-130 kDa due to glycosylation.
- Gene ID
- 3902
- UniProt
- P18627
- Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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