MME Protein (Fc Tag)
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- Target See all MME Proteins
- MME (Membrane Metallo-Endopeptidase (MME))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This MME protein is labelled with Fc Tag.
- Purpose
- Recombinant Human CD10 protein with N-terminal human Fc
- Specificity
- HFc (Glu99-Ala330) CD10 (Tyr52-Trp750)
- Characteristics
- Extracellular Domain Protein
- Purification
- Purified from cell culture supernatant by affinity chromatography
- Purity
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
- Top Product
- Discover our top product MME Protein
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Membrane Metallo-Endopeptidase (MME) (AA 52-750) protein (His tag)
MME Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Membrane Metallo-Endopeptidase (MME) (AA 52-750) protein (His tag)MME Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Membrane Metallo-Endopeptidase (MME) (AA 53-750) protein (His tag)MME Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Membrane Metallo-Endopeptidase (MME) (AA 1-750) protein (GST tag)MME Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Membrane Metallo-Endopeptidase (MME) (AA 145-250) protein (GST tag)MME Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Membrane Metallo-Endopeptidase (MME) protein (His tag)MME Origin: Rat Host: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- MME (Membrane Metallo-Endopeptidase (MME))
- Alternative Name
- CD10 (MME Products)
- Synonyms
- CALLA Protein, CD10 Protein, NEP Protein, SFE Protein, 6030454K05Rik Protein, C85356 Protein, Nep Protein, neprilysin Protein, membrane metalloendopeptidase Protein, membrane metallo endopeptidase Protein, membrane metallo-endopeptidase Protein, MME Protein, Mme Protein
- Background
- The protein encoded by this gene is a type II transmembrane glycoprotein and a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). The encoded protein is present on leukemic cells of pre-B phenotype, which represent 85 % of cases of ALL. This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues. The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin.
- Molecular Weight
- predicted molecular mass of 106.1 kDa after removal of the signal peptide.
- Gene ID
- 4311
- UniProt
- P08473
- Pathways
- RTK Signaling, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Smooth Muscle Cell Migration
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