CNR1 Protein (AA 1-116) (Fc Tag)
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- Target See all CNR1 Proteins
- CNR1 (Cannabinoid Receptor 1 (CNR1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-116
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This CNR1 protein is labelled with Fc Tag.
- Purpose
- Recombinant Human CB1 protein with C-terminal human Fc
- Specificity
- CB1 (Met1-Gln116) hFc (Glu99-Ala330)
- Characteristics
- Extracellular Domain Protein
- Purification
- Purified from cell culture supernatant by affinity chromatography
- Purity
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
- Top Product
- Discover our top product CNR1 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- CNR1 (Cannabinoid Receptor 1 (CNR1))
- Alternative Name
- CB1 (CNR1 Products)
- Synonyms
- CANN6 Protein, CB-R Protein, CB1 Protein, CB1A Protein, CB1K5 Protein, CB1R Protein, CNR Protein, SKR6R Protein, cnr1-A Protein, cannabinoid receptor 1 Protein, cannabinoid receptor 1 (brain) Protein, cannabinoid receptor 1 (brain) S homeolog Protein, CNR1 Protein, Cnr1 Protein, cnr1 Protein, cnr1.S Protein
- Background
- This gene encodes one of two cannabinoid receptors. The cannabinoids, principally delta-9-tetrahydrocannabinol and synthetic analogs, are psychoactive ingredients of marijuana. The cannabinoid receptors are members of the guanine-nucleotide-binding protein (G-protein) coupled receptor family, which inhibit adenylate cyclase activity in a dose-dependent, stereoselective and pertussis toxin-sensitive manner. The two receptors have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. Multiple transcript variants encoding two different protein isoforms have been described for this gene.
- Molecular Weight
- predicted molecular mass of 39.3 kDa after removal of the signal peptide.The apparent molecular mass of CB1-hFc is 55-70 kDa due to glycosylation.
- Gene ID
- 1268
- UniProt
- P21554
- Pathways
- Feeding Behaviour
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