TIGIT Protein (AA 22-141) (mFc Tag)
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- Target See all TIGIT Proteins
- TIGIT (T Cell Immunoreceptor with Ig and ITIM Domains (TIGIT))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 22-141
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This TIGIT protein is labelled with mFc Tag.
- Application
- ELISA
- Purpose
- Recombinant human TIGIT Protein with C-terminal mouse Fc tag
- Specificity
- TIGIT (Met22-Pro141) mFc (Pro99-Lys330)
- Characteristics
- Extracellular Domain Protein
- Purification
- Purified from cell culture supernatant by affinity chromatography
- Purity
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
- Top Product
- Discover our top product TIGIT Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- TIGIT (T Cell Immunoreceptor with Ig and ITIM Domains (TIGIT))
- Alternative Name
- TIGIT (TIGIT Products)
- Synonyms
- VSIG9 Protein, VSTM3 Protein, WUCAM Protein, ENSMUSG00000071552 Protein, Vstm3 Protein, RGD1563191 Protein, T-cell immunoreceptor with Ig and ITIM domains Protein, T cell immunoreceptor with Ig and ITIM domains Protein, TIGIT Protein, Tigit Protein
- Background
- This gene encodes a member of the PVR (poliovirus receptor) family of immunoglobin proteins. The product of this gene is expressed on several classes of T cells including follicular B helper T cells (TFH). The protein has been shown to bind PVR with high affinity, this binding is thought to assist interactions between TFH and dendritic cells to regulate T cell dependent B cell responses.
- Molecular Weight
- predicted molecular mass of 39.24 kDa after removal of the signal peptide.The apparent molecular mass of TIGIT-mFc is 40-53 kDa due to glycosylation.
- Gene ID
- 201633
- UniProt
- Q495A1
- Pathways
- Cancer Immune Checkpoints
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