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P-Selectin Protein (AA 42-771) (Fc Tag)

SELP Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Catalog No. ABIN6961139
  • Target See all P-Selectin (SELP) Proteins
    P-Selectin (SELP) (Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 42-771
    Origin
    • 15
    • 12
    • 4
    • 2
    • 2
    Human
    Source
    • 14
    • 9
    • 5
    • 4
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This P-Selectin protein is labelled with Fc Tag.
    Purpose
    Recombinant human SELP protein with C-terminal human Fc tag
    Specificity
    SELP (Trp42-Aal771) hFc (Glu99-Ala330)
    Characteristics
    Extracellular Domain Protein
    Purification
    Purified from cell culture supernatant by affinity chromatography
    Purity
    The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
    Top Product
    Discover our top product SELP Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    Expiry Date
    12 months
  • Target
    P-Selectin (SELP) (Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP))
    Alternative Name
    SELP (SELP Products)
    Synonyms
    PSELECT Protein, CD62 Protein, CD62P Protein, GMP140 Protein, GRMP Protein, LECAM3 Protein, PADGEM Protein, PSEL Protein, GMP-140 Protein, Grmp Protein, selectin P Protein, selectin, platelet Protein, Selp Protein, SELP Protein
    Background
    This gene encodes a 140 kDa protein that is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. This protein redistributes to the plasma membrane during platelet activation and degranulation and mediates the interaction of activated endothelial cells or platelets with leukocytes. The membrane protein is a calcium-dependent receptor that binds to sialylated forms of Lewis blood group carbohydrate antigens on neutrophils and monocytes. Alternative splice variants may occur but are not well documented.
    Molecular Weight
    predicted molecular mass of 106.1 kDa after removal of the signal peptide.The apparent molecular mass of SELP-hFc is 130-150 kDa due to glycosylation.
    Gene ID
    6403
    UniProt
    P16109
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