AXL Protein (AA 26-449) (His tag)
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- Target See all AXL Proteins
- AXL (AXL Receptor tyrosine Kinase (AXL))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 26-449
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This AXL protein is labelled with His tag.
- Application
- ELISA
- Purpose
- Recombinant human AXL protein with C-terminal 6xHis tag
- Specificity
- AXL (Ala26-Pro449) 6xHis tag
- Characteristics
- Extracellular Domain Protein
- Purification
- Purified from cell culture supernatant by affinity chromatography
- Purity
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
- Top Product
- Discover our top product AXL Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- AXL (AXL Receptor tyrosine Kinase (AXL))
- Alternative Name
- AXL (AXL Products)
- Synonyms
- JTK11 Protein, UFO Protein, AI323647 Protein, Ark Protein, Tyro7 Protein, Ufo Protein, AXL receptor tyrosine kinase Protein, Axl receptor tyrosine kinase Protein, AXL Protein, Axl Protein
- Background
- The protein encoded by this gene is a member of the Tyro3-Axl-Mer (TAM) receptor tyrosine kinase subfamily. The encoded protein possesses an extracellular domain which is composed of two immunoglobulin-like motifs at the N-terminal, followed by two fibronectin type-III motifs. It transduces signals from the extracellular matrix into the cytoplasm by binding to the vitamin K-dependent protein growth arrest-specific 6 (Gas6). This gene may be involved in several cellular functions including growth, migration, aggregation and anti-inflammation in multiple cell types. Alternative splicing results in multiple transcript variants of this gene.
- Molecular Weight
- predicted molecular mass of 46.6 kDa after removal of the signal peptide.
- Gene ID
- 558
- UniProt
- P30530
- Pathways
- RTK Signaling, Cellular Response to Molecule of Bacterial Origin
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