SLAMF6 Protein (AA 22-226) (mFc-His Tag)
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- Target See all SLAMF6 Proteins
- SLAMF6 (SLAM Family Member 6 (SLAMF6))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 22-226
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This SLAMF6 protein is labelled with mFc-His Tag.
- Purpose
- Recombinant human NTB-A protein with C-terminal mouse Fc and 6xHis tag
- Specificity
- NTB-A (Gln22-Met226) mFc (Pro99-Lys330) 6xHis tag
- Characteristics
- Extracellular Domain Protein
- Purification
- Purified from cell culture supernatant by affinity chromatography
- Purity
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
- Top Product
- Discover our top product SLAMF6 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- SLAMF6 (SLAM Family Member 6 (SLAMF6))
- Alternative Name
- NTB-A (SLAMF6 Products)
- Synonyms
- SLAMF6 Protein, CD352 Protein, KALI Protein, KALIb Protein, Ly108 Protein, NTB-A Protein, NTBA Protein, SF2000 Protein, KAL1 Protein, KAL1b Protein, RGD1561848 Protein, SLAM family member 6 Protein, SLAMF6 Protein, Slamf6 Protein
- Background
- The protein encoded by this gene is a type I transmembrane protein, belonging to the CD2 subfamily of the immunoglobulin superfamily. This encoded protein is expressed on Natural killer (NK), T, and B lymphocytes. It undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases (SHPs). It functions as a coreceptor in the process of NK cell activation. It can also mediate inhibitory signals in NK cells from X-linked lymphoproliferative patients. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
- Molecular Weight
- predicted molecular mass of 50.1 kDa after removal of the signal peptide.
- Gene ID
- 114836
- UniProt
- Q96DU3
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