CD226 Protein (CD226) (AA 19-247) (mFc-His Tag)
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- Target See all CD226 Proteins
- CD226
- Protein Type
- Recombinant
- Protein Characteristics
- AA 19-247
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This CD226 protein is labelled with mFc-His Tag.
- Application
- ELISA
- Purpose
- Recombinant human DNAM-1 protein with C-terminal mouse Fc and 6xHis tag
- Specificity
- DNAM-1 (Glu19-Asn247) mFc (Pro99-Lys330) 6xHis tag
- Characteristics
- Extracellular Domain Protein
- Purification
- Purified from cell culture supernatant by affinity chromatography
- Purity
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
- Top Product
- Discover our top product CD226 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- CD226
- Alternative Name
- DNAM-1 (CD226 Products)
- Synonyms
- CD226 Protein, cd226 Protein, zgc:158817 Protein, BC051526 Protein, DNAM-1 Protein, DNAM1 Protein, Pta1 Protein, TLiSA1 Protein, PTA1 Protein, CD226 molecule Protein, CD226 antigen Protein, CD226 Protein, cd226 Protein, Cd226 Protein
- Background
- This gene encodes a glycoprotein expressed on the surface of NK cells, platelets, monocytes and a subset of T cells. It is a member of the Ig-superfamily containing 2 Ig-like domains of the V-set. The protein mediates cellular adhesion of platelets and megakaryocytic cells to vascular endothelial cells. The protein also plays a role in megakaryocytic cell maturation. Alternative splicing results in multiple transcript variants.
- Molecular Weight
- predicted molecular mass of 53.5 kDa after removal of the signal peptide.
- Gene ID
- 10666
- UniProt
- Q15762
- Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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