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CD70 Protein (mFc-His Tag)

CD70 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. ELISA
Catalog No. ABIN6961112
  • Target See all CD70 Proteins
    CD70 (CD70 Molecule (CD70))
    Protein Type
    Recombinant
    Origin
    • 29
    • 8
    • 1
    • 1
    • 1
    Human
    Source
    • 24
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This CD70 protein is labelled with mFc-His Tag.
    Application
    ELISA
    Purpose
    Recombinant human CD70 protein with N-terminal mouse Fc and C-terminal 6xHis tag
    Specificity
    MFc (Pro99-Lys330) CD70 (Gln39-Pro193) 6xHis
    Characteristics
    Extracellular Domain Protein
    Purification
    Purified from cell culture supernatant by affinity chromatography
    Purity
    The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
    Top Product
    Discover our top product CD70 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    Expiry Date
    12 months
  • Target
    CD70 (CD70 Molecule (CD70))
    Alternative Name
    CD70 (CD70 Products)
    Synonyms
    CD27LG Protein, Cd27l Protein, Tnfsf7 Protein, CD27L Protein, TNFSF7 Protein, CD70 antigen Protein, CD70 molecule Protein, Cd70 molecule Protein, Cd70 Protein, CD70 Protein
    Background
    The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis.
    Molecular Weight
    predicted molecular mass of 45.6 kDa after removal of the signal peptide.
    Gene ID
    970
    UniProt
    P32970
    Pathways
    Cancer Immune Checkpoints
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