BCMA Protein (AA 1-54) (mFc Tag)
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- Target See all BCMA (TNFRSF17) Proteins
- BCMA (TNFRSF17) (Tumor Necrosis Factor Receptor Superfamily, Member 17 (TNFRSF17))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-54
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This BCMA protein is labelled with mFc Tag.
- Application
- ELISA
- Purpose
- Recombinant human BCMA protein with C-terminal mouse Fc tag
- Specificity
- BCMA (Met1-Ala54) mFc (Pro99-Lys330)
- Characteristics
- Extracellular Domain Protein
- Purification
- Purified from cell culture supernatant by affinity chromatography
- Purity
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
- Biological Activity Comment
- EC50=3.163
- Top Product
- Discover our top product TNFRSF17 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- BCMA (TNFRSF17) (Tumor Necrosis Factor Receptor Superfamily, Member 17 (TNFRSF17))
- Alternative Name
- BCMA (TNFRSF17 Products)
- Synonyms
- TNFRSF17 Protein, BCM Protein, BCMA Protein, CD269 Protein, TNFRSF13A Protein, Tnfrsf13 Protein, Tnfrsf13a Protein, TNF receptor superfamily member 17 Protein, tumor necrosis factor receptor superfamily, member 17 Protein, Tnfrsf17 Protein, TNFRSF17 Protein
- Background
- B-cell maturation protein (BCMA or BCM), is also known as Tumor necrosis factor receptor superfamily member 17 (TNFRSF17), which is encoded by the TNFRSF17 gene. TNFRSF17 is a cell surface receptor of the TNF receptor superfamily which recognizes B-cell activating factor (BAFF). This receptor is expressed in immune organs and mature B cell lines. BCMA promotes B-cell survival and plays a role in the regulation of humoral immunity. BCMA can activate NF-kappa-B and JNK.
- Molecular Weight
- predicted molecular mass of 32.1 kDa after removal of the signal peptide.
- Gene ID
- 608
- UniProt
- Q02223
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