CXCL10 Protein (AA 22-98)
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- Target See all CXCL10 Proteins
- CXCL10 (Chemokine (C-X-C Motif) Ligand 10 (CXCL10))
- Protein Type
- Recombinant
- Biological Activity
- Active
- Protein Characteristics
- AA 22-98
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Application
- Cell Migration Assay (CMA)
- Sequence
- VPLSRTVRCT CISISNQPVN PRSLEKLEII PASQFCPRVE IIATMKKKGE KRCLNPESKA IKNLLKAVSK ERSKRSP
- Characteristics
- Recombinant Human CXCL10 (IP-10)
- Endotoxin Level
- <0.01 EU per 1μg of the protein by the LAL method
- Biological Activity Comment
- EC50 = 6.3 nM determined by Migration Assay in cells expressing recombinant CXCR3
- Top Product
- Discover our top product CXCL10 Protein
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Chemokine (C-X-C Motif) Ligand 10 (CXCL10) (AA 27-91) protein (His tag)
CXCL10 Origin: Cynomolgus Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by Tris-Bis PAGE
Chemokine (C-X-C Motif) Ligand 10 (CXCL10) (AA 22-98) protein (Fc Tag)CXCL10 Origin: Cynomolgus Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Chemokine (C-X-C Motif) Ligand 10 (CXCL10) (AA 1-98) protein (GST tag)CXCL10 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Chemokine (C-X-C Motif) Ligand 10 (CXCL10) (AA 22-98), (full length) protein (His tag)CXCL10 Origin: Human Host: Escherichia coli (E. coli) Recombinant 90 % ELISA
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Spin tube prior to resuspending. Recommended at 100 μg/mL in sterile water
- Storage
- -20 °C,-80 °C
- Storage Comment
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12 months from date of receipt, -20 to -70 °C as supplied.
Suggest to use immediately after reconstitution
1 month at -20 to -70 °C under sterile conditions after reconstitution. - Expiry Date
- 12 months
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- Target
- CXCL10 (Chemokine (C-X-C Motif) Ligand 10 (CXCL10))
- Alternative Name
- CXCL10 (IP-10) (CXCL10 Products)
- Synonyms
- CXCL10 Protein, C7 Protein, IFI10 Protein, INP10 Protein, IP-10 Protein, SCYB10 Protein, crg-2 Protein, gIP-10 Protein, mob-1 Protein, CRG-2 Protein, IP10 Protein, Ifi10 Protein, Scyb10 Protein, C-X-C motif chemokine ligand 10 Protein, C-X-C motif chemokine 10 Protein, chemokine (C-X-C motif) ligand 10 Protein, CXCL10 Protein, cxl10 Protein, Cxcl10 Protein
- Background
- CXCL10 (IP-10) was originally identified as an IFN-gamma-inducible gene in endothelial, fibroblasts and monocytes cells. IP-10 is considered a member of the CXC chemokine subfamily from its protein sequence which includes the four conserved cysteine residues present in CXC chemokines. IP-10 signals through the CXCR3 receptor to selectively attract Th1 lymphocytes and monocytes. It also has angiostatic and mitogenic properties on vascular smooth muscle cells. A diverse population of cell types rapidly increases transcription of mRNA encoding IP-10, which suggests that gamma-induced protein may be a key mediator of the IFNG/IFN-gamma response.
- Molecular Weight
- 8.646 kDa
- UniProt
- P02778
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