CCL7 Protein (AA 24-99) (Biotin)
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- Target See all CCL7 Proteins
- CCL7 (Chemokine (C-C Motif) Ligand 7 (CCL7))
- Protein Type
- Recombinant
- Biological Activity
- Active
- Protein Characteristics
- AA 24-99
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This CCL7 protein is labelled with Biotin.
- Application
- Cell Migration Assay (CMA)
- Sequence
- QPVGINTSTT CCYRFINKKI PKQRLESYRR TTSSHCPREA VIFKTKLDKE ICADPTQKWV QDFMKHLDKK TQTPKL
- Characteristics
- Biotininylated Recombinant Human CCL7 (MCP-3)
- Purity
- > 97 % by SDS PAGE
- Endotoxin Level
- <0.01 EU per 1μg of the protein by the LAL method
- Biological Activity Comment
- EC50 = 1.4-2.6 nM determined by migration assay with cells expressing recombinant CCR2
- Top Product
- Discover our top product CCL7 Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Spin tube prior to resuspending. Recommended at 100 μg/mL in sterile water
- Storage
- -20 °C,-80 °C
- Storage Comment
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12 months from date of receipt, -20 to -70 °C as supplied.
Suggest to use immediately after reconstitution
1 month at -20 to -70 °C under sterile conditions after reconstitution. - Expiry Date
- 12 months
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- Target
- CCL7 (Chemokine (C-C Motif) Ligand 7 (CCL7))
- Alternative Name
- CCL7 (MCP-3) (CCL7 Products)
- Synonyms
- CCL7 Protein, FIC Protein, MARC Protein, MCP-3 Protein, MCP3 Protein, NC28 Protein, SCYA6 Protein, SCYA7 Protein, Scya7 Protein, fic Protein, marc Protein, mcp3 Protein, C-C motif chemokine ligand 7 Protein, chemokine (C-C motif) ligand 7 Protein, CCL7 Protein, Ccl7 Protein
- Background
- Monocyte chemotactic protein 3 (MCP-3/CCL7) is secreted by monocytes and certain tumor cell lines. It is a chemoattractant for monocytes and other leukocytes. MCP-3 binds and signals through several chemokine receptors including CCR1, CCR2, CCR3, and appears to be an antagonist for CCR5.
- Molecular Weight
- 11.374 kDa
- UniProt
- P80098
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