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CCL7 Protein (AA 24-99) (Biotin)

CCL7 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 97 % by SDS PAGE CMA Active
Catalog No. ABIN6952211
  • Target See all CCL7 Proteins
    CCL7 (Chemokine (C-C Motif) Ligand 7 (CCL7))
    Protein Type
    Recombinant
    Biological Activity
    Active
    Protein Characteristics
    AA 24-99
    Origin
    • 7
    • 5
    • 4
    Human
    Source
    • 13
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This CCL7 protein is labelled with Biotin.
    Application
    Cell Migration Assay (CMA)
    Sequence
    QPVGINTSTT CCYRFINKKI PKQRLESYRR TTSSHCPREA VIFKTKLDKE ICADPTQKWV QDFMKHLDKK TQTPKL
    Characteristics
    Biotininylated Recombinant Human CCL7 (MCP-3)
    Purity
    > 97 % by SDS PAGE
    Endotoxin Level
    <0.01 EU per 1μg of the protein by the LAL method
    Biological Activity Comment
    EC50 = 1.4-2.6 nM determined by migration assay with cells expressing recombinant CCR2
    Top Product
    Discover our top product CCL7 Protein
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Spin tube prior to resuspending. Recommended at 100 μg/mL in sterile water
    Storage
    -20 °C,-80 °C
    Storage Comment
    12 months from date of receipt, -20 to -70 °C as supplied.
    Suggest to use immediately after reconstitution
    1 month at -20 to -70 °C under sterile conditions after reconstitution.
    Expiry Date
    12 months
  • Target
    CCL7 (Chemokine (C-C Motif) Ligand 7 (CCL7))
    Alternative Name
    CCL7 (MCP-3) (CCL7 Products)
    Synonyms
    CCL7 Protein, FIC Protein, MARC Protein, MCP-3 Protein, MCP3 Protein, NC28 Protein, SCYA6 Protein, SCYA7 Protein, Scya7 Protein, fic Protein, marc Protein, mcp3 Protein, C-C motif chemokine ligand 7 Protein, chemokine (C-C motif) ligand 7 Protein, CCL7 Protein, Ccl7 Protein
    Background
    Monocyte chemotactic protein 3 (MCP-3/CCL7) is secreted by monocytes and certain tumor cell lines. It is a chemoattractant for monocytes and other leukocytes. MCP-3 binds and signals through several chemokine receptors including CCR1, CCR2, CCR3, and appears to be an antagonist for CCR5.
    Molecular Weight
    11.374 kDa
    UniProt
    P80098
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