CCL27 Protein (AA 25-112)
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- Target See all CCL27 Proteins
- CCL27 (Chemokine (C-C Motif) Ligand 27 (CCL27))
- Protein Type
- Recombinant
- Biological Activity
- Active
- Protein Characteristics
- AA 25-112
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Application
- Cell Migration Assay (CMA)
- Sequence
- FLLPPSTACC TQLYRKPLSD KLLRKVIQVE LQEADGDCHL QAFVLHLAQR SICIHPQNPS LSQWFEHQER KLHGTLPKLN FGMLRKMG
- Characteristics
- Recombinant Human CCL27 (CTACK)
- Purity
- > 97 % by SDS PAGE
- Endotoxin Level
- <0.01 EU per 1μg of the protein by the LAL method
- Biological Activity Comment
- EC50 = 34 nM determined by Migration Assay in cells expressing recombinant CCR10
- Top Product
- Discover our top product CCL27 Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Spin tube prior to resuspending. Recommended at 100 μg/mL in sterile water
- Storage
- -20 °C,-80 °C
- Storage Comment
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12 months from date of receipt, -20 to -70 °C as supplied.
Suggest to use immediately after reconstitution
1 month at -20 to -70 °C under sterile conditions after reconstitution. - Expiry Date
- 12 months
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- Target
- CCL27 (Chemokine (C-C Motif) Ligand 27 (CCL27))
- Alternative Name
- CCL27 (CTACK) (CCL27 Products)
- Synonyms
- ALP Protein, ILC Protein, CTACK Protein, ESkine Protein, CCL27 Protein, CTAK Protein, ESKINE Protein, PESKY Protein, SCYA27 Protein, AW558992 Protein, Ccl27 Protein, Scya27 Protein, Scya27a Protein, C-C motif chemokine ligand 27 Protein, uncharacterized LOC508933 Protein, chemokine (C-C motif) ligand 27A Protein, Ccl27 Protein, CCL27 Protein, LOC508933 Protein, Ccl27a Protein
- Background
- Cutaneous T-cell-attracting chemokine (CTACK/CCL27) is a ligand for cell surface receptor CCR10. It is responsible for chemotaxis of skin-homing memory T cells during cutaneous inflammation. Interestingly, after CCR10-mediated internalization, CTACK, as well as a non-secreted splice variant of the same gene, can reach the nucleus and modulate transcription and cell behavior.
- Molecular Weight
- 10.149kDa
- UniProt
- Q9Y4X3
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