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CCL27 Protein (AA 25-112)

CCL27 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 97 % by SDS PAGE CMA Active
Catalog No. ABIN6952170
  • Target See all CCL27 Proteins
    CCL27 (Chemokine (C-C Motif) Ligand 27 (CCL27))
    Protein Type
    Recombinant
    Biological Activity
    Active
    Protein Characteristics
    AA 25-112
    Origin
    • 4
    • 4
    Human
    Source
    • 7
    • 1
    Escherichia coli (E. coli)
    Application
    Cell Migration Assay (CMA)
    Sequence
    FLLPPSTACC TQLYRKPLSD KLLRKVIQVE LQEADGDCHL QAFVLHLAQR SICIHPQNPS LSQWFEHQER KLHGTLPKLN FGMLRKMG
    Characteristics
    Recombinant Human CCL27 (CTACK)
    Purity
    > 97 % by SDS PAGE
    Endotoxin Level
    <0.01 EU per 1μg of the protein by the LAL method
    Biological Activity Comment
    EC50 = 34 nM determined by Migration Assay in cells expressing recombinant CCR10
    Top Product
    Discover our top product CCL27 Protein
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Spin tube prior to resuspending. Recommended at 100 μg/mL in sterile water
    Storage
    -20 °C,-80 °C
    Storage Comment
    12 months from date of receipt, -20 to -70 °C as supplied.
    Suggest to use immediately after reconstitution
    1 month at -20 to -70 °C under sterile conditions after reconstitution.
    Expiry Date
    12 months
  • Target
    CCL27 (Chemokine (C-C Motif) Ligand 27 (CCL27))
    Alternative Name
    CCL27 (CTACK) (CCL27 Products)
    Background
    Cutaneous T-cell-attracting chemokine (CTACK/CCL27) is a ligand for cell surface receptor CCR10. It is responsible for chemotaxis of skin-homing memory T cells during cutaneous inflammation. Interestingly, after CCR10-mediated internalization, CTACK, as well as a non-secreted splice variant of the same gene, can reach the nucleus and modulate transcription and cell behavior.
    Molecular Weight
    10.149kDa
    UniProt
    Q9Y4X3
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