CCL19 Protein (AA 22-98) (Biotin)
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- Target See all CCL19 Proteins
- CCL19 (Chemokine (C-C Motif) Ligand 19 (CCL19))
- Protein Type
- Recombinant
- Biological Activity
- Active
- Protein Characteristics
- AA 22-98
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This CCL19 protein is labelled with Biotin.
- Application
- Cell Migration Assay (CMA)
- Sequence
- GTNDAEDCCL SVTQKPIPGY IVRNFHYLLI KDGCRVPAVV FTTLRGRQLC APPDQPWVER IIQRLQRTSA KMKRRSS
- Characteristics
- Biotininylated Recombinant Human CCL19 (MIP-3beta)
- Purity
- > 97 % by SDS PAGE
- Endotoxin Level
- <0.01 EU per 1μg of the protein by the LAL method
- Biological Activity Comment
- EC50 = 18-25 nM determined by migration assay with cells expressing recombinant CCR7
- Top Product
- Discover our top product CCL19 Protein
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Chemokine (C-C Motif) Ligand 19 (CCL19) (AA 26-108) protein (His tag)
CCL19 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Chemokine (C-C Motif) Ligand 19 (CCL19) (AA 22-98) protein (Fc Tag)CCL19 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Chemokine (C-C Motif) Ligand 19 (CCL19) (AA 22-98) (Active) proteinCCL19 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 97 % by SDS PAGE CMA Active
Chemokine (C-C Motif) Ligand 19 (CCL19) (AA 22-98) protein (T7 tag)CCL19 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % by SDS - PAGE SDS
Chemokine (C-C Motif) Ligand 19 (CCL19) (AA 1-98) protein (GST tag)CCL19 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Spin tube prior to resuspending. Recommended at 100 μg/mL in sterile water
- Storage
- -20 °C,-80 °C
- Storage Comment
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12 months from date of receipt, -20 to -70 °C as supplied.
Suggest to use immediately after reconstitution
1 month at -20 to -70 °C under sterile conditions after reconstitution. - Expiry Date
- 12 months
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- Target
- CCL19 (Chemokine (C-C Motif) Ligand 19 (CCL19))
- Alternative Name
- CCL19 (MIP-3beta) (CCL19 Products)
- Synonyms
- CKb11 Protein, ELC Protein, MIP-3b Protein, MIP3B Protein, SCYA19 Protein, CCL19 Protein, Scya19 Protein, exodus-3 Protein, C-C motif chemokine ligand 19 Protein, chemokine (C-C motif) ligand 19 Protein, CCL19 Protein, ccl19 Protein, Ccl19 Protein
- Background
- Macrophage inflammatory protein-3-beta (MIP-3beta/CCL19), also known as EBI1 ligand chemokine (ELC), directs chemotaxis of dendritic cells, and certain B- and T- lymphocytes, but not monocytes or granulocytes. It is constituitively expressed in thymus and lymph nodes and binds specifically to target cells expressing the receptor CCR7. Being a homeostatic chemokine, its primary physiological role is considered to be in the normal recirculation and homing of lymphocyte. However, MIP-3beta could also be proinflammatory, and is implicated in the post-HIV infection responses.
- Molecular Weight
- 11.219 kDa
- UniProt
- Q99731
- Pathways
- Positive Regulation of Immune Effector Process
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