CCL14 Protein (AA 28-93)
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- Target See all CCL14 Proteins
- CCL14 (Chemokine (C-C Motif) Ligand 14 (CCL14))
- Protein Type
- Recombinant
- Biological Activity
- Active
- Protein Characteristics
- AA 28-93
- Origin
- Human
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Source
- Escherichia coli (E. coli)
- Sequence
- GPYHPSECCF TYTTYKIPRQ RIMDYYETNS QCSKPGIVFI TKRGHSVCTN PSDKWVQDYI KDMKEN
- Characteristics
- Recombinant Human CCL14 (HCC-1)
- Purity
- > 97 % by SDS PAGE
- Endotoxin Level
- <0.01 EU per 1μg of the protein by the LAL method
- Biological Activity Comment
- EC50 = 0.1-0.4 nM determined by Migration Assay in cells expressing recombinant CCR1
- Top Product
- Discover our top product CCL14 Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Spin tube prior to resuspending. Recommended at 100 μg/mL in sterile water
- Storage
- -20 °C,-80 °C
- Storage Comment
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12 months from date of receipt, -20 to -70 °C as supplied.
Suggest to use immediately after reconstitution
1 month at -20 to -70 °C under sterile conditions after reconstitution. - Expiry Date
- 12 months
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- Target
- CCL14 (Chemokine (C-C Motif) Ligand 14 (CCL14))
- Alternative Name
- CCL14 (HCC-1) (CCL14 Products)
- Synonyms
- CCL14 Protein, CC-1 Protein, CC-3 Protein, CKB1 Protein, HCC-1 Protein, HCC-1(1-74) Protein, HCC-1/HCC-3 Protein, HCC-3 Protein, MCIF Protein, NCC-2 Protein, NCC2 Protein, SCYA14 Protein, SCYL2 Protein, SY14 Protein, C-C motif chemokine ligand 14 Protein, C-C motif chemokine 14 Protein, chemokine (C-C motif) ligand 14 Protein, CCL14 Protein, Ccl14 Protein, LOC480603 Protein, LOC101115044 Protein
- Background
- Hemofiltrate CC chemokine-1(HCC-1/CCL14) is endogeneously expressed by numerous tissues. Upon processing of the N terminal residues of the full length HCC-1 by the uPA-plasmin system, the active form of HCC-1 (made by ChemoTactics) is a strong agonist for CCR1, CCR5 and to a lesser extent CCR3, and causes chemotaxis of different types of leukocytes. The active form of HCC-1 is also shown as a potent inhibitor of HIV entry.
- Molecular Weight
- 7.801 kDa
- UniProt
- Q16627
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