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IGSF11 Protein (AA 23-241) (Fc Tag)

IGSF11 Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Catalog No. ABIN6938885
  • Target See all IGSF11 Proteins
    IGSF11 (Immunoglobulin Superfamily, Member 11 (IGSF11))
    Protein Type
    Recombinant
    Biological Activity
    Active
    Protein Characteristics
    AA 23-241
    Origin
    • 7
    • 1
    • 1
    • 1
    Human
    Source
    • 5
    • 2
    • 1
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This IGSF11 protein is labelled with Fc Tag.
    Purity
    >95 % as determined by SDS-PAGE.
    Endotoxin Level
    Less than 1.0 EU per μg by the LAL method.
    Top Product
    Discover our top product IGSF11 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    Tris with Glycine, Arginine and NaCl,  pH 7.5
    Storage
    -20 °C
  • Target
    IGSF11 (Immunoglobulin Superfamily, Member 11 (IGSF11))
    Alternative Name
    VSIG3 (IGSF11 Products)
    Synonyms
    sc:d812 Protein, seurat Protein, BT-IgSF Protein, CT119 Protein, CXADRL1 Protein, Igsf13 Protein, VSIG3 Protein, 1700025L02Rik Protein, immunoglobulin superfamily member 11 Protein, immunoglobulin superfamily member 11 L homeolog Protein, immunoglobulin superfamily, member 11 Protein, IGSF11 Protein, igsf11 Protein, igsf11.L Protein, Igsf11 Protein
    Background
    VSIG3, also known as IGSF11, BT-IgSF, and CLMP, is a homophilic adhesion molecule that preferentially expressed in the brain. The function of VSIG3 is to stimulate cell growth through homophilic interactions. In clinical, the VSIG3 has been reported to as a novel target for cancer immunotherapy of gastrointestinal and hepatocellular carcinomas. In addition, VSIG-3 is also a ligand of B7 family member VISTA/PD-1H and inhibits human T-cell functions through a novel VSIG-3/VISTA pathway. VSIG-3/VISTA co-inhibitory pathway may provide new strategies for the treatment of human cancers and autoimmune disorders.
    Molecular Weight
    49.7 kDa
    NCBI Accession
    NP_001015887
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