FGL1 Protein (AA 23-312) (AVI tag,Fc Tag,Biotin)
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- Target See all FGL1 Proteins
- FGL1 (Fibrinogen-Like 1 (FGL1))
- Protein Type
- Recombinant
- Biological Activity
- Active
- Protein Characteristics
- AA 23-312
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This FGL1 protein is labelled with AVI tag,Fc Tag,Biotin.
- Sequence
- AA 23-312
- Specificity
- Biotinylation of this product is performed using Avitag™ technology. Briefly, the single lysine residue in the Avitag is enzymatically labeled with biotin.
- Purity
- >95 % as determined by SDS-PAGE.
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product FGL1 Protein
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- Comment
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Ready-to-use AvitagTM biotinylated protein:
The product is exclusively produced using the AvitagTM technology. Briefly, a unique 15 amino acid peptide, the Avi tag, is introduced into the recombinant protein during expression vector construction. The single lysine residue in the Avi tag is enzymatically biotinylated by the E. Coli biotin ligase BirA.
This single-point enzymatic labeling technique brings many advantages for commonly used binding assays. The biotinylation happens on the lysine residue of Avi tag, and therefore does NOT interfere with the target protein's natural binding activities. In addition, when immobilized on an avidin-coated surface, the protein orientation is uniform because the position of the Avi tag in the protein is precisely controlled. - Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Tris with Glycine, Arginine and NaCl, pH 7.5
- Handling Advice
- Please avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
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- Target
- FGL1 (Fibrinogen-Like 1 (FGL1))
- Alternative Name
- FGL1 (FGL1 Products)
- Synonyms
- MGC84748 Protein, FGL1 Protein, DKFZp470A2333 Protein, Frep1 Protein, Lfire1 Protein, HFREP1 Protein, HP-041 Protein, LFIRE-1 Protein, LFIRE1 Protein, Mfire1 Protein, fibrinogen like 1 L homeolog Protein, fibrinogen like 1 Protein, fibrinogen-like 1 Protein, fibrinogen-like protein 1 Protein, fgl1.L Protein, FGL1 Protein, Fgl1 Protein
- Background
- Fibrinogen-like protein 1(FGL1) is also known as HP-041, Hepassocin, HFREP-1, LFIRE-1. The protective effect of fibrinogen-like protein 1 (FGL1) in liver injury has previously been reported. However, studies have shown that FGL1 may be a predictor of GC patients and a target for GC therapy. Immunocytochemical studies revealed that fgl1 selectively binds to defective spermatozoa in the cauda epididymidis. Northern blot analysis and in situ hybridization demonstrated the high expression of fgl1 in the principal cells of the proximal cauda epididymidis. Immunofluorescence analysis using mouse fibrotic lung tissues suggested that fibrotic regions showed increased expressions of Gtse1 and Fgl1, Gtse1 and Fgl1 are suggested to be novel targets for radiation-induced lung fibrosis.
- Molecular Weight
- 62.1 kDa
- NCBI Accession
- NP_004458
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