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IL-17A/F Protein

Rockland 010-001-v56-0005 IL-17A/F Origin: Mouse Host: Escherichia coli (E. coli) Recombinant 98,00% SDS
Rockland
Catalog No. ABIN6700942
Supplier Product No.: 010-001-v56-0005
  • Target See all IL-17A/F Proteins
    IL-17A/F (Interleukin-17 A/F Heterodimer (IL-17A/F))
    Protein Type
    Recombinant
    Origin
    • 7
    • 4
    • 3
    Mouse
    Source
    • 8
    • 5
    • 1
    Escherichia coli (E. coli)
    Application
    SDS-PAGE (SDS)
    Supplier Product No.
    010-001-v56-0005
    Supplier
    Rockland
    Purpose
    Mouse Interleukin-17AF Heterodimer Recombinant Protein
    Purification
    Interleukin-17AF Heterodimer purity was determined to be greater than 98% as determined by HpLC, analysis by UV-Spectroscopy at 280nm, and by reducing and non-reducing SDS-pAGE.
    Purity
    98,00%
    Endotoxin Level
    Measured by LAL is typically ≤ 1 EU/μg protein.
    Biological Activity Comment
    Measured by LAL is typically ≤ 1 EU/μg protein.
    Top Product
    Discover our top product IL-17A/F Protein
  • Application Notes

    Other: User Optimized

    Application_Note: Interleukin-17AF Heterodimer Recombinant Protein has been tested by SDS-PAGE and is suitable as a control for polyclonal or monoclonal anti-Interleukin-17AF Heterodimer in immunological assays.

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution

    Reconstitution_Buffer: Restore with deionized water (or equivalent)

    Reconstitution_Volume: 5 μL (5-50 μL)

    Buffer

    Buffer: 0.1 % Trifluoroacetic acid

    Stabilizer: None

    Preservative
    Without preservative
    Storage
    4 °C,-20 °C
    Storage Comment
    Store vial at 4° C prior to restoration. Dilute only prior to immediate use. Maintain sterility. This product DOES NOT contain preservative. DO NOT VORTEX. We recommend adding a carrier protein such as HSA or BSA to 0.1% (i.e. 1.0 mg/mL). For best results aliquot contents and freeze at -20° C or colder. Avoid cycles of freezing and thawing. Centrifuge vial before each opening to dislodge contents from the cap and to clarify if contents are not clear after standing at room temperature.
    Expiry Date
    6 months
  • Target
    IL-17A/F (Interleukin-17 A/F Heterodimer (IL-17A/F))
    Alternative Name
    IL-17AF Heterodimer (IL-17A/F Products)
    Background

    Synonyms: IL17 heterodimer, IL17AF heterodimer, CTLA-8 ML-1 dimer, Interleukin 17AF, Interleukin-17AF heterodimer

    Background: Interleukin-17AF (IL-17AF) is a member of the IL-17 family of proteins produced by a subset of T cells, called Th17, following stimulation with IL-23. Since IL-17AF is thought to signal through the IL-17R receptor, its biological function is similar to that of IL-17A in that it induces the production of a variety of chemokines, in addition to airway neutrophilia. In regard to these functions, IL-17AF has less activity than the IL-17A homodimer but, greater activity than the IL-17F homodimer. Human and rat IL-17AF both show activity on mouse cells. Recombinant mouse IL-17AF is a non-glycosylated, disulfide-linked heterodimer. It is containing one IL-17A subunit and one IL-17F subunit, with a total of 271 amino acids and an molecular weight of 30.7 kDa.

    UniProt
    Q62386
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