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SCYL1 Protein (GST tag)

Rockland 009-001-t26s SCYL1 Origin: Human Host: Insect cells (Sf9) Recombinant >95% WB
Rockland
Catalog No. ABIN6700489
Supplier Product No.: 009-001-t26s
  • Target See all SCYL1 Proteins
    SCYL1 (SCY1-Like 1 (SCYL1))
    Protein Type
    Recombinant
    Origin
    • 3
    • 2
    Human
    Source
    • 3
    • 2
    Insect cells (Sf9)
    Purification tag / Conjugate
    This SCYL1 protein is labelled with GST tag.
    Application
    Western Blotting (WB)
    Supplier Product No.
    009-001-t26s
    Supplier
    Rockland
    Purpose
    SCYL1 recombinant protein-GST fusion protein
    Purification
    Recombinant human SCYL1 (1-556) was expressed by baculovirus in Sf9 insect cells using an N-Terminal Glutathione-S-Transferase fusion protein. The purity was determined to be >95% by densitometry.
    Purity
    >95%
    Top Product
    Discover our top product SCYL1 Protein
  • Application Notes

    Western_Blot_Dilution: User Optimized

    Application_Note: SCYL1 Protein is suitable for use in Western Blot. Expect a band approximately ~85 kDa on specific lysates or tissues. Specific conditions for reactivity should be optimized by the end user.

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.1 μg/μL
    Buffer
    SCYL1 Protein is stored in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store product at -70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
    Expiry Date
    12 months
  • Target
    SCYL1 (SCY1-Like 1 (SCYL1))
    Alternative Name
    SCYL1 (SCYL1 Products)
    Background

    Synonyms: GKLP, HT019, NKTL, NTKL, P105, TAPK, TEIF, TRAP, N-terminal kinase-like protein, Coated vesicle-associated kinase of 90 kDa, SCY1-like protein 1, Telomerase regulation-associated protein, Telomerase transcriptional element-interacting factor, Teratoma-associated tyrosine kinase

    Background: SCYL1 is a transcriptional regulator belonging to the SCY1-like family of kinase-like proteins. SCYL1 has a divergent N-terminal kinase domain that is thought to be catalytically inactive, and can bind specific DNA sequences through its C-terminal domain. SCYL1 activates transcription of the telomerase reverse transcriptase and DNA polymerase beta genes. SCYL1 forms multimers following transfection into COS-7 cells (1). A SCYL1 binding protein has been identified that co-localized with SCYL1 in cytoplasm and shows ubiquitous expression (2). SCYL1 Protein is ideal for investigators involved in Signaling Proteins, Cellular Proteins, Inflammation, Invasion/Metastasis, and Neurobiology research.

    NCBI Accession
    NM_020680
    Pathways
    p53 Signaling
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